Tracking Research on Hemoglobin-Based Oxygen Carriers: A Scientometric Analysis and In-Depth Review

被引：3
|
作者：
Zhang, Qi [1 ]
Ma, Yue-Xiang [1 ]
Dai, Zheng [1 ]
Zhang, Bin [1 ]
Liu, Shan-Shou [1 ]
Li, Wen-Xiu [1 ]
Fu, Chuan -Qing [1 ]
Wang, Qian-Mei [1 ]
Yin, Wen [1 ,2 ]
机构：
[1] Air Force Med Univ, Xijing Hosp, Dept Emergency, Xian, Peoples R China
[2] Air Force Med Univ, Xijing Hosp, Dept Orthopaed Surg, 127 Changlexi Rd, Xian 710032, Shaanxi, Peoples R China
来源：
DRUG DESIGN DEVELOPMENT AND THERAPY | 2023年 / 17卷
关键词：
blood substitutes; trauma; hemorrhagic shock; organ preservation; anemia; risk management; HUMAN POLYMERIZED HEMOGLOBIN; BLOOD SUBSTITUTES; BOVINE HEMOGLOBIN; MYOCARDIAL-INFARCTION; GLUTAMER-250; BOVINE; LACTATE CLEARANCE; CELL SUBSTITUTES; JEHOVAH-WITNESS; NITRIC-OXIDE; STORAGE;
D O I：
10.2147/DDDT.S422770
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Numerous studies on the formulation and clinical applications of novel hemoglobin-based oxygen carriers (HBOCs) are reported in the scientific literature. However, there are fewer scientometric analysis related to HBOCs. Here, we illustrate recent studies on HBOCs using both a scientometric analysis approach and a scope review method. We used the former to investigate research on HBOCs from 1991 to 2022, exploring the current hotspots and research trends, and then we comprehensively analyzed the relationship between concepts based on the keyword analysis. The evolution of research fields, knowledge structures, and research topics in which HBOCs located are revealed by scientometric analysis. The elucidation of type, acting mechanism, potential clinical practice, and adverse effects of HBOCs helps to clarify the prospects of this biological agent. Scientometrics analyzed 1034 publications in this research field, and these findings provide a promising roadmap for further study.
引用
收藏
页码：2549 / 2571
页数：23
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