Effectiveness of a video-based exercise program on nutritional status and quality of life of peritoneal dialysis patients: A pilot randomized controlled trial

Objective: To evaluate the ef-fectiveness of a video-based exercise pro-gram on nutritional status and quality of life (QOL) of peritoneal dialysis (PD) patients. Materials and methods: Participants satisfy-ing the inclusion and exclusion criteria were recruited and divided into the intervention group and the control group. The interven-tion group received video-based exercise based on a manual advocated by the Na-tional Kidney Foundation, while the control group received routine exercise guidance. Their nutritional indicators and the Quality of Life Scale for Peritoneal Dialysis patients (QLSPD) scores were collected and analyzed. Results: No adverse events occurred dur-ing the study. Baseline data between the two groups were comparable, and there were no significant differences in body mass index (BMI) (t = 0.214, p = 0.831), tri-ceps skin fold thickness (TSF) (t = 0.407, p = 0.685), arm muscle circumference (AMC) (t = 0.310, p = 0.757), grip strength (Gs) (t = 0.557, p = 0.579), calf circumfer-ence (Cc) (t = 0.441, p = 0.660), serum al-bumin (Alb) (t = 0.261, p = 0.795), prealbu-min (PA) (t = 0.218, p = 0.828), hemoglobin (Hb) (t = 0.114, p = 0.909), triglyceride (TG) (t = 0.192, p = 0.848), total cholesterol (TC)(t = 0.092, p = 0.927), low-density lipopro-tein (LDL) (t = 0.124, p = 0.902), high -den-sity lipoprotein (HDL) (t = 0.265, p = 0.792), blood urea nitrogen (BUN) (t = 0.540, p = 0.590), serum creatinine (SCr) (t = 0.255, p = 0.799), total urea clearance index (Kt/V) (t = 0.958, p = 0.340), total creatinine clear-ance rate (Ccr) (t = 0.166, p = 0.868), pro-tein equivalent of nitrogen appearance (nPNA) (t = 0.240, p = 0.811), and QLSPD scores(p > 0.05) between the two groups at the baseline measures. However, after 12 weeks of intervention, the AMC (t = 2.993, p = 0.003) and Cc (t = 2.811, p = 0.006) of the intervention group improved signifi-cantly compared with the control group. The BMI (t = 2.068, p = 0.041) and TSF (t = 2.578, p = 0.011) showed a trend of im-provement compared with baseline. And the intervention group scored less in body physiology function (t = 7.084, p < 0.001), disease factors (t = 13.336, p < 0.001), men-tal state (t = 9.555, p<0.001), and social role (t = 5.156, p < 0.001) components, while their satisfaction hardly changed (t = 0.240, p = 0.811). Conclusion: The video-based ex-ercise intervention is safe and can remark-ably improve the nutritional status and QOL of PD patients.