Understanding of surface chemistry of silica-based nanomaterials contributes to the design of safe and efficacious nanomedicine

被引：2
|
作者：
Li, Jiulong [1 ,2 ]
Liu, Xiangsheng [3 ]
Ma, Kai [4 ]
Liu, Yanyan [1 ,2 ]
Meng, Huan [1 ,2 ]
机构：
[1] CAS Key Lab Biomed Effects Nanomat & Nanosafety, Beijing 100190, Peoples R China
[2] CAS Ctr Excellence Nanosci Natl Ctr Nanosci & Tech, Beijing 100190, Peoples R China
[3] Chinese Acad Sci, Zhejiang Canc Hosp, Hangzhou Inst Med HIM, Hangzhou 310022, Zhejiang, Peoples R China
[4] Tsinghua Univ, Dept Biomed Engn, Beijing 100084, Peoples R China
来源：
MATTER | 2023年 / 6卷 / 08期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1016/j.matt.2023.06.023
中图分类号：
T [工业技术];
学科分类号：
08 ;
摘要：
Silica exhibits exceptional properties for biomedical applications, including drug delivery. Although bulk silica is generally safe, the distinct characteristics of nanosized silica necessitate further inves-tigation. Varying manufacturing conditions generate different silica surfaces and chemically distinct silanol groups. Recent advance-ments have demonstrated the utility of experimental and in silico approaches in characterizing silica surface properties that deter-mine the fate and outcomes of nano silica/bio interactions.
引用
收藏
页码：2564 / 2567
页数：4
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