Sotorasib in KRAS G12C-mutated NSCLC: A multicenter real-world experience from the expanded access program in Germany

被引:2
|
作者
Althoff, F. C. [1 ]
Stratmann, J. A. [1 ]
Doebel, P. [1 ]
Hunerlituerkoglu, A. N. [2 ]
Frost, N. [3 ,4 ]
Christopoulos, P. [5 ]
Zum Bueschenfelde, C. Meyer [6 ]
Alt, J. [7 ]
Webendoerfer, M. [8 ]
Kaldune, S. [9 ]
Tritchkova, G. [10 ]
Waller, C. F. [11 ]
Braess, J. [12 ]
Kopp, H-G. [13 ]
Grohe, C. [14 ]
Schumann, C. [15 ]
Griesinger, F. [16 ]
Kuon, J. B. [17 ]
Sebastian, M.
Reinmuth, N. [18 ]
机构
[1] Johannes Wolfgang Goethe Univ, Haematol Oncol, Univ Klinikum Frankfurt, Frankfurt, Germany
[2] Helios Klinikum Krefeld, Hematol Oncol, Krefeld, Germany
[3] Univ Klin, Dept Infect Dis & Pneumonol, Berlin, Germany
[4] Charite Campus Virchow Klinikum, Berlin, Germany
[5] Thoraxklin Heidelberg gGmbH, Dept Oncol Thorac Tumors, Heidelberg, Germany
[6] ViDia Karlsruhe Diakonissenkrankenhaus, Hematol Oncol, Karlsruhe, Germany
[7] Univ Med Mainz, Med Klin Poliklin 3, Mainz, Germany
[8] Univ Klinikum Essen, Med Oncol, Essen, Germany
[9] RoMed Klinikum Rosenheim, Med Klin, Rosenheim, Germany
[10] Tech Univ Dresden, Internal Med, Carl Gustav Carus Fac Med, Dresden, Germany
[11] Univ Klinikum Freiburg, Hematol Oncol & Stem Cell Transplantat, Klin Innere Med Hamatol Onkol & Stammzelltranspla, Freiburg, Germany
[12] St John Gods Hosp, Hematol Med Oncol, Regensburg, Germany
[13] Robert Bosch Kran Kenhaus, Dept Hematol Oncol, Stuttgart, Germany
[14] ELK Berlin Chest Hosp, Pneumol, Evangel Lungenklin, Berlin, Germany
[15] Klinikum Kempten Oberallgaeu gGmbH, Klin Pneumol Thoraxonkol Schlaf & Beamtungsmed, Kempten, Germany
[16] Pius Hosp, Dept Oncol, Oldenburg, Germany
[17] SLK Kliniken Heilbronn GmbH, Thorac Oncol Dept, Heilbronn, Germany
[18] Asklepios Fachklinikum, Thorac Oncol, Gauting, Germany
关键词
D O I
10.1016/j.annonc.2023.09.2437
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
1405P
引用
收藏
页数:1
相关论文
共 50 条
  • [21] Sotorasib in KRAS G12C-mutated advanced non-small cell lung cancer (aNSCLC): Overall survival (OS) data from the global expanded access program (EAP study-436)
    Novello, S.
    Maimon, N.
    Stevenson, J. P.
    Petty, W.
    Ferreira, C. G. M.
    Morbeck, I.
    Zer, A.
    Bauman, J. R.
    Kalmadi, S.
    Xia, C.
    Meloni, A.
    Varrieur, T.
    Awad, M.
    JOURNAL OF THORACIC ONCOLOGY, 2023, 18 (04) : S40 - S41
  • [22] Prolonged Cancer Control With Adagrasib in Patients With Metastatic, KRAS G12C-Mutated NSCLC After Sotorasib-Induced Hepatotoxicity: A Case Report
    Stratton, Natalie
    Thompson, Jonathan
    JTO CLINICAL AND RESEARCH REPORTS, 2024, 5 (04):
  • [23] Use of sotorasib in KRAS p. G12C mutated NSCLC: a case report
    Barot, Hasti
    Evans, Joanne
    Mohammed, Waleed
    Power, Danielle
    LUNG CANCER, 2022, 165 : S77 - S77
  • [24] Real-world effectiveness and tolerability of sotorasib in patients with KRAS G12C-mutated metastatic non-small cell lung cancer: The IFCT-2102 Lung KG12Ci study
    Wislez, M.
    Mascaux, C.
    Cadranel, J.
    Thomas, Q. D.
    Ricordel, C.
    Swalduz, A.
    Pichon, E.
    Veillon, R.
    Gounant, V.
    Rousseau-Bussac, G.
    Madroszyk, A.
    Daniel, C.
    Ravoire, M.
    Metivier, A. -C
    Fournel, P.
    Missy, P.
    Morin, F.
    Guisier, F.
    Westeel, V.
    EUROPEAN JOURNAL OF CANCER, 2025, 219
  • [25] Sotorasib Shows Intracranial Activity in Patients with KRAS G12C-Mutated Adenocarcinoma of the Lung and Untreated Active Brain Metastases
    Koster, Kira-Lee
    Appenzeller, Christina
    Lauber, Arno
    Fruh, Martin
    Schmid, Sabine
    CASE REPORTS IN ONCOLOGY, 2022, 15 (02): : 720 - 725
  • [26] Prognostic implication of KRAS G12C mutation in a real-world KRAS mutated stage IV NSCLC cohort treated with immunotherapy in the Netherlands
    Noordhof, Anneloes L.
    Swart, Esther M.
    Damhuis, Ronald A. M.
    Hendriks, Lizza E. L.
    Kunst, Peter W. A.
    Aarts, Mieke J.
    Van Geffen, Wouter H.
    EUROPEAN RESPIRATORY JOURNAL, 2023, 62
  • [27] Prognostic Implication of KRAS G12C Mutation in a Real-World KRAS-Mutated Stage IV NSCLC Cohort Treated With Immunotherapy in The Netherlands
    Noordhof, Anneloes L.
    Swart, Esther M.
    Damhuis, Ronald A. M.
    Hendriks, Lizza E. L.
    Kunst, Peter W. A.
    Aarts, Mieke J.
    van Geffen, Wouter H.
    JTO CLINICAL AND RESEARCH REPORTS, 2023, 4 (09):
  • [28] Sotorasib with panitumumab in chemotherapy-refractory KRAS G12C-mutated colorectal cancer: a phase 1b trial
    Kuboki Y.
    Fakih M.
    Strickler J.
    Yaeger R.
    Masuishi T.
    Kim E.J.
    Bestvina C.M.
    Kopetz S.
    Falchook G.S.
    Langer C.
    Krauss J.
    Puri S.
    Cardona P.
    Chan E.
    Varrieur T.
    Mukundan L.
    Anderson A.
    Tran Q.
    Hong D.S.
    Nature Medicine, 2024, 30 (1) : 265 - 270
  • [29] NURSING EXPERIENCE WITH PATIENTS RECEIVING SOTORASIB FOR KRAS G12C-MUTATED SOLID TUMORS: FOLLOW-UP FROM THE PHASE 1/2 CODEBREAK 100 STUDY
    Dozier, Askia
    Fitzpatrick, Victoria
    Liu, Dazhi
    Hull, Jennifer
    Varrieur, Tracy
    McGuire, Lauren
    ONCOLOGY NURSING FORUM, 2022, 49 (02) : 22 - 23
  • [30] COST PER RESPONDER ANALYSIS COMPARING ADAGRASIB AND SOTORASIB IN PATIENTS WITH KRAS G12C-MUTATED PREVIOUSLY TREATED NON-SMALL CELL LUNG CANCER (NSCLC)
    Berardi, A.
    Laurie, M.
    Theriou, C.
    Orsini, I
    Bouwmeester, W.
    Gao, S.
    Korytowsky, B.
    VALUE IN HEALTH, 2023, 26 (12) : S119 - S120