Squalene epoxidase promotes pancreatic ductal adenocarcinoma tumorigenesis and drives gemcitabine resistance by activating the PI3K-Akt pathway

被引：0
|
作者：
Liu, Lei [1 ]
Xu, Hui [2 ]
Huang, Xinyang [1 ]
Li, Weilin [3 ]
Jin, Yixun [1 ]
Zhang, Minmin [1 ]
Wang, Lifu [1 ]
Zou, Duowu [1 ]
机构：
[1] Shanghai Jiao Tong Univ, Ruijin Hosp, Sch Med, Shanghai, Peoples R China
[2] Zhejiang Univ, Affiliated Hosp 1, Coll Med, Hangzhou, Zhejiang, Peoples R China
[3] Harvard Med Sch, Beth Israel Deaconess Med Ctr, Boston, MA USA
来源：
GUT | 2023年 / 72卷 / SUPPL_1期
关键词：
D O I：
10.1136/gutjnl-2023-IDDF.68
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
IDDF2023-A
引用
收藏
页码：A76 / A77
页数：2
相关论文
共 50 条
  • [21] LncRNA AB209630 inhibits gemcitabine resistance cell proliferation by regulating PI3K/AKT signaling in pancreatic ductal adenocarcinoma
    Wang, Libin
    Wang, Feng
    Na, Li
    Yu, Jingjing
    Huang, Liya
    Meng, Zhi-Qiang
    Chen, Zhen
    Chen, Hao
    Ming, Liu-Lu
    Hua, Yong-Qiang
    CANCER BIOMARKERS, 2018, 22 (01) : 169 - 174
  • [22] RNF7 Facilitated the Tumorigenesis of Pancreatic Cancer by Activating PI3K/Akt Signaling Pathway
    Hua, Hao
    Xie, Huahua
    Zheng, Jian
    Lei, Linhan
    Deng, Zilei
    Yu, Chao
    OXIDATIVE MEDICINE AND CELLULAR LONGEVITY, 2023, 2023
  • [23] Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway
    Xusheng Zhang
    Bendong Chen
    Kejun Liu
    Yongxin Ma
    Yimin Liu
    Hongcai Zhou
    Peng Wei
    Discover Oncology, 14
  • [24] Infection with COVID-19 promotes the progression of pancreatic cancer through the PI3K-AKT signaling pathway
    Zhang, Xusheng
    Chen, Bendong
    Liu, Kejun
    Ma, Yongxin
    Liu, Yimin
    Zhou, Hongcai
    Wei, Peng
    DISCOVER ONCOLOGY, 2023, 14 (01)
  • [25] PDGFBB facilitates tumorigenesis and malignancy of lung adenocarcinoma associated with PI3K-AKT/MAPK signaling
    He, Xiu-Ying
    Zheng, Yue-Xiang
    Yang, Hui-Si
    Yu, Hong-Zhou
    Xia, Qing-Jie
    Wang, Ting-Hua
    SCIENTIFIC REPORTS, 2024, 14 (01)
  • [26] PDGFBB facilitates tumorigenesis and malignancy of lung adenocarcinoma associated with PI3K-AKT/MAPK signaling
    He Xiu-Ying
    Zheng Yue-Xiang
    Yang Hui-Si
    Yu Hong-Zhou
    Xia Qing-Jie
    Wang Ting-Hua
    Scientific Reports, 14
  • [27] Postconditioning - A form of "modified reperfusion" protects the myocardium by activating the PI3K-Akt pathway
    Tsang, A
    Hausenloy, DJ
    Mocanu, MM
    Yellon, DM
    CIRCULATION, 2004, 110 (17) : 167 - 168
  • [28] RRP9 promotes gemcitabine resistance in pancreatic cancer via activating AKT signaling pathway
    Zhiqi Zhang
    Haitao Yu
    Wenyan Yao
    Na Zhu
    Ran Miao
    Zhiquan Liu
    Xuwei Song
    Chunhua Xue
    Cheng Cai
    Ming Cheng
    Ke Lin
    Dachuan Qi
    Cell Communication and Signaling, 20
  • [29] Increased Semaphorin 3c Promotes Tumor Growth and Metastasis in Pancreatic Ductal Adenocarcinoma by Inactivating PI3K/AKT Signaling Pathway
    Xu, X.
    Wang, H.
    PANCREAS, 2016, 45 (10) : 1547 - 1547
  • [30] Epiplakin1 promotes the progression of esophageal squamous cell carcinoma by activating the PI3K-AKT signaling pathway
    Qiao, Zhongshi
    Dai, Chengcheng
    Wang, Zhiqian
    Wang, Zifan
    Wang, Zheng
    Zhang, Tongsong
    Niu, Wenjing
    Ma, Xuezhen
    THORACIC CANCER, 2022, 13 (08) : 1117 - 1125
12345