Depletion of SIV-specific CD8+T cells does not alter viral load kinetics during SIV infection

被引:0
|
作者
Simpson, Jennifer C. [1 ]
Starke, Carly E. [1 ,2 ]
Ortiz, Alexandra M. [1 ]
Ransier, Amy [3 ]
Darko, Sam [3 ]
Douek, Daniel C. [3 ]
Llewellyn-Lacey, Sian [4 ]
Price, David A. [4 ]
Brenchley, Jason M. [1 ]
机构
[1] NIAID, Barrier Immun Sect, Lab Viral Dis, NIH, Bethesda, MD USA
[2] Fred Hutchinson Canc Ctr, Stem Cell & Gene Therapy Program, Seattle, WA USA
[3] NIH, Human Immunol Sect, Vaccine Res Ctr, Bethesda, MD USA
[4] Cardiff Univ, Div Infect & Immun, Sch Med, Cardiff, Wales
关键词
D O I
暂无
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
引用
收藏
页码:325 / 325
页数:1
相关论文
共 50 条
  • [21] SIV-Specific CD8+T Cells are Enriched in Female Genital Mucosa of Rhesus Macaques and Express Receptors for Inflammatory Chemokines
    Cromwell, Mandy A.
    Carville, Angela
    Mansfield, Keith
    Klumpp, Sherry
    Westmoreland, Susan V.
    Lackner, Andrew A.
    Johnson, R. Paul
    AMERICAN JOURNAL OF REPRODUCTIVE IMMUNOLOGY, 2011, 65 (03) : 242 - 247
  • [22] Transduction of SIV-Specific TCR Genes into Rhesus Macaque CD8+ T Cells Conveys the Ability to Suppress SIV Replication
    Barsov, Eugene V.
    Trivett, Matthew T.
    Minang, Jacob T.
    Sun, Haosi
    Ohlen, Claes
    Ott, David E.
    PLOS ONE, 2011, 6 (08):
  • [23] ROLE OF CD8+T CELLS DURING ACUTE INFECTION IN CYNOMOLGUS MACAQUES CONTROLLING SIV REPLICATION
    Passaes, Caroline
    Versmisse, Pierre
    Sylla, Naya
    Torres, Claire
    Cassan, Christelle
    Targat, Brice
    Cosma, Antonio
    Le Grand, Roger
    Pancino, Gianfranco
    Dereuddre-Bosquet, Nathalie
    Vaslin, Bruno
    Saez-Cirion, Asier
    JOURNAL OF MEDICAL PRIMATOLOGY, 2015, 44 (05) : 320 - 321
  • [24] Immunotoxin-mediated depletion of Gag-specific CD8+T cells undermines natural control of SIV
    Simpson, Jennifer
    Starke, Carly E.
    Ortiz, Alexandra M.
    Ransier, Amy
    Darko, Sam
    Llewellyn-Lacey, Sian
    Fennessey, Christine M.
    Keele, Brandon F.
    Douek, Daniel C.
    Price, David A.
    Brenchley, Jason M.
    JCI INSIGHT, 2024, 9 (14)
  • [25] Multi-omics analysis at single-cell level of SIV-specific CD8+T cells in ART-suppressed SIV-infected rhesus macaques
    Lee, Michelle Y. -H.
    Mopuri, Rohini
    Lapp, Stacey
    Metz, Amanda M.
    Govindu, Vasanthi
    Trenkle, Aaron D. Silva
    Karunakaran, Kirti A.
    Ton, Thang
    Kwong, Gabriel A.
    Altman, John D.
    Su, Lishan
    Amara, Rama R.
    Bosinger, Steven E.
    JOURNAL OF MEDICAL PRIMATOLOGY, 2023, 52 (05) : 314 - 315
  • [26] SIV-specific CD8+ T cells are clonotypically distinct across lymphoid and mucosal tissues
    Starke, Carly E.
    Vinton, Carol L.
    Ladell, Kristin
    McLaren, James E.
    Ortiz, Alexandra M.
    Mudd, Joseph C.
    Flynn, Jacob K.
    Lai, Stephen H.
    Wu, Fan
    Hirsch, Vanessa M.
    Darko, Samuel
    Douek, Daniel C.
    Price, David A.
    Brenchley, Jason M.
    JOURNAL OF CLINICAL INVESTIGATION, 2020, 130 (02): : 789 - 798
  • [28] Maturation of protective immunity induced by SIVΔnef correlates with differential expression of transcription factors in SIV-specific CD8+ T cells
    JM Billingsley
    PA Rajakumar
    NC Salisch
    YV Kuzmichev
    HS Hong
    MA Connole
    RK Reeves
    H Kang
    W Li
    RP Johnson
    Retrovirology, 9 (Suppl 2)
  • [29] Induction of Unique Subset of Follicular Homing SIV-specific CD8 T Cells by Vaccination Is Associated with Enhanced Control of Pathogenic SIV
    Mylvaganam, Geetha
    Reddy, Pradeep
    Rios, Daniel
    Mohammad, Hadia
    Gangadhara, Sailaja
    Turner-Styles, Tiffany
    Iyer, Smita
    Hicks, Sakeenah
    Tharp, Gregory
    Mavigner, Maud
    Chahroudi, Ann
    Bosinger, Steve
    Williams, Ifor
    Skinner, Pamela
    Velu, Vijayakumar
    Amara, Rama
    AIDS RESEARCH AND HUMAN RETROVIRUSES, 2016, 32 : 85 - 85
  • [30] Contribution of antigen-specific CD4+ T cells to the generation of SIV-specific CD8+ memory cells
    Vaccari, Monica
    Tsai, Wen-Po
    Hryniewicz, Anna
    Nacsa, Janos
    Heraud, Jean-Michel
    Doster, Melvin N.
    Panicali, Dennis
    Schmitz, Joern E.
    Reimann, Keith A.
    Franchini, Genoveffa
    JOURNAL OF MEDICAL PRIMATOLOGY, 2006, 35 (4-5) : 283 - 283