Synthesis of 2-Aryl-7-Methyl-1-Phenyl-4-Selenoxo-1,4-Dihydro-Pyrano[4,3-d]Pyrimidin-5-One via a Three-Component Condensation

被引：2

作者：

Talaei, Hamed ^{[1
]}

Mosslemin, Mohammad H. ^{[1
]}

Hassanabadi, Alireza ^{[2
]}

Mohebat, Razieh ^{[1
]}

机构：

[1] Islamic Azad Univ, Dept Chem, Yazd Branch, Yazd, Iran

[2] Islamic Azad Univ, Dept Chem, Zahedan Branch, Zahedan, Iran

来源：

POLYCYCLIC AROMATIC COMPOUNDS | 2023年 / 43卷 / 05期

关键词：

Aroyl chlorides; 6-methyl-4-phenylamino-pyran-2-one; potassium selenocyanate; N-methylimidazole; pyrano[4; 3-d]pyrimidin; SELENIUM-CONTAINING HETEROCYCLES;

D O I：

10.1080/10406638.2022.2086890

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reaction between 6-methyl-4-phenylamino-pyran-2-one and aroyl chlorides with potassium selenocyanate in the presence of catalytic amounts of N-methylimidazole under solvent-free conditions provided a simple and efficient one-pot route for the synthesis of 2-aryl-7-methyl-1-phenyl-4-selenoxo-1,4-dihydro-pyrano[4,3-d]pyrimidin-5-one. This new protocol offers advantages such as mild reaction conditions, short reaction time, easy work-up, high yields of biological active products and does not involve any hazardous solvent.

引用

页码：4299 / 4304

页数：6

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