MOG-IgG positive optic neuritis after SARS-CoV-2 infection

被引:9
|
作者
Gilardi, Marta [1 ]
Cortese, Antonio [2 ]
Ferraro, Elisabetta [2 ]
Rispoli, Marco [1 ]
Sadun, Riccardo [3 ]
Altavista, Maria Concetta [4 ]
Sadun, Federico [1 ]
机构
[1] Presidio Osped Oftalm, Neuroophthalmol Unit, Piazzale Eroi 11, I-00136 Rome, Italy
[2] Presidio Osped San Filippo Neri, Multiple Sclerosis Ctr, Rome, Italy
[3] Univ Cattolica Sacro Cuore Sch Med, Rome, Italy
[4] Presidio Osped San Filippo Neri, Neurol Unit, Rome, Italy
关键词
optic neuritis < NEURO OPHTHALMOLOGY; neuro imaging < NEURO OPHTHALMOLOGY; immunology < IMMUNOLOGY; infections disease/aids < NEURO OPHTHALMOLOGY; optic neuropathy < NEURO OPHTHALMOLOGY;
D O I
10.1177/11206721221136319
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
Background :Many neurologic complications have been described after severe acute respiratory syndrome Coronavirus-2 (SARS-CoV-2) including atypical cases of optic neuritis (ON), positive to myelin oligodendrocyte glycoprotein (MOG) IgG. Objective: To report a case of MOG-IgG-associated ON and discuss why SARS-CoV-2 infection could be a potential trigger. Methods: Retrospective single case report. Results We report a case of ON with positive MOG-IgG developed 15 days after presentation of SARS-CoV-2 infection. Conclusion: This report suggests that SARS-CoV-2 infection may have triggered autoantibodies production against MOG leading to ON.
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页码:NP87 / NP90
页数:4
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