Targeting Myeloid Epithelial Tyrosine Kinase (MERTK) Receptor in Acute Myeloid Leukemia Using a Novel Antibody Drug Conjugate, Rgx-019-MMAE

被引：1
|
作者：
Tyagi, Anudishi [1 ]
Siddiqui, Maryam
Kurth, Isabel [2 ]
Takeda, Shugaku [2 ]
Eckstrom, Amanda [1 ]
Borgman, Jenny [1 ]
Maiti, Abhishek [3 ]
Battula, Venkata Lokesh [1 ]
机构：
[1] Univ Texas MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA
[2] Inspirna Inc, New York, NY USA
[3] MD Anderson Canc Ctr, Dept Leukemia, Houston, TX USA
来源：
BLOOD | 2023年 / 142卷
关键词：
D O I：
10.1182/blood-2023-175048
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页数：3
相关论文
共 50 条
  • [31] MBRC-101: a novel antibody-drug conjugate (ADC) targeting the tyrosine kinase receptor EphA5
    Staquicini, Fernanda I.
    Tang, Fenny H.
    de Oliveira, Vanessa
    Staquicini, Daniela I.
    Wu, Yongjian
    Barnhart, Kirstin F.
    Parsons, J. Kellogg
    Arap, Wadih
    Chen, Isan
    Pasqualini, Renata
    CANCER RESEARCH, 2024, 84 (06)
  • [32] The FLT3 tyrosine kinase receptor ITD mutation controls its expression and drug resistance in acute myeloid leukemia
    Alqahtani, Taha
    MacEwan, David
    CANCER RESEARCH, 2024, 84 (06)
  • [33] The Myeloid Cell Surface Receptor IREM-1: A Novel Monoclonal Antibody Target for Acute Myeloid Leukemia (AML)
    Zhao, Xiaoxian
    Korver, Wouter
    Singh, Shweta
    Pardoux, Cecile
    Hsi, Eric D.
    Abo, Arie
    BLOOD, 2008, 112 (11) : 1009 - 1009
  • [34] A novel immunoliposome mediated by CD123 antibody targeting to acute myeloid leukemia cells
    Wang, Yin
    Liu, Furong
    Wang, Qiantao
    Xiang, Honglin
    Jin, Hui
    Li, Hui
    Mao, Shengjun
    INTERNATIONAL JOURNAL OF PHARMACEUTICS, 2017, 529 (1-2) : 531 - 542
  • [35] FLT3 Tyrosine Kinase Inhibition as a Paradigm for Targeted Drug Development in Acute Myeloid Leukemia
    Grunwald, Michael R.
    Levis, Mark J.
    SEMINARS IN HEMATOLOGY, 2015, 52 (03) : 193 - 199
  • [36] Targeting the BCR-ABL tyrosine kinase in chronic myeloid leukemia as a model of rational drug design in cancer
    Zamecnikova, Adriana
    EXPERT REVIEW OF HEMATOLOGY, 2010, 3 (01) : 45 - 56
  • [37] Targeting drug-resistant acute myeloid leukemia (AML) cells using novel casein kinase II (CK2) inhibitor
    Duke, Koby
    Mercer, Katherine
    Rajaiah, Rajesh
    Daniyal, Muhammad
    Qiu, Yi
    Purandare, Ashok
    Uzun, Yasin
    Zhang, Lijun
    Klink, Morgann
    Gowda, Chandrika
    CANCER RESEARCH, 2023, 83 (07)
  • [38] An overview on the role of FLT3-tyrosine kinase receptor in acute myeloid leukemia: biology and treatment
    Grafone, Tiziana
    Palmisano, Michela
    Nicci, Chiara
    Storti, Sergio
    ONCOLOGY REVIEWS, 2012, 6 (01) : 64 - 74
  • [39] The amount of c-kit receptor tyrosine: Kinase predicts outcome in acute myeloid leukemia (AML).
    Del Poeta, G
    Venditti, A
    Maurillo, L
    Buccisano, F
    Abruzzese, E
    Tamburini, A
    Suppo, G
    Del Principe, MI
    Scornajenghi, KA
    Bruno, A
    Cox, MC
    Masi, M
    Amadori, S
    BLOOD, 2001, 98 (11) : 716A - 716A
  • [40] High expression of the receptor tyrosine kinase Tie-1 in acute myeloid leukemia and myelodysplastic syndrome
    Verstovsek, S
    Estey, E
    Manshouri, T
    Keating, M
    Kantarjian, H
    Giles, FJ
    Albitar, M
    LEUKEMIA & LYMPHOMA, 2001, 42 (03) : 511 - 516
12345