How to select healthy sperm for intracytoplasmic sperm injection in samples with high sperm DNA fragmentation?

被引：6
|
作者：
Garrido, Nicolas [1 ,2 ]
Gul, Murat [1 ,3 ]
Jindal, Sunil [1 ,4 ]
Vogiatzi, Paraskevi [1 ,5 ]
Saleh, Ramadan [1 ,6 ]
Durairajanayagam, Damayanthi [1 ,7 ]
Parmegiani, Lodovico [8 ]
Boitrelle, Florence [1 ,9 ,10 ]
Colpi, Giovanni M. [1 ,11 ]
Agarwal, Ashok [1 ,2 ,12 ]
机构：
[1] Global Androl Forum, Moreland Hills, OH USA
[2] Inst Invest Sanitaria La Fe IIS La Fe, IVI Fdn, Valencia, Spain
[3] Selcuk Univ, Sch Med, Dept Urol, Konya, Turkiye
[4] Jindal Hosp & Fertil Ctr, Dept Androl & Reprod Med, Meerut, India
[5] Fertil & Reprod Hlth Diagnost Ctr, Andromed Hlth & Reprod, Athens, Greece
[6] Sohag Univ, Fac Med, Dept Dermatol Venereol & Androl, Sohag, Egypt
[7] Univ Teknol MARA, Fac Med, Dept Physiol, Bangi, Selangor, Malaysia
[8] Androl & IVF Ctr NextFertil Procrea, Lugano, Switzerland
[9] Poissy Hosp, Reprod Biol, Fertil Preservat, Androl,CECOS, Poissy, France
[10] Paris Saclay Univ, UVSQ, INRAE, BREED, Jouy En Josas, France
[11] Next Fertil Procrea, Lugano, Switzerland
[12] Amer Ctr Reprod Med, Cleveland, OH 45069 USA
来源：
PANMINERVA MEDICA | 2023年 / 65卷 / 02期
关键词：
Sperm injections; intracytoplasmic; Infertility; male; DNA fragmentation; DENSITY GRADIENT CENTRIFUGATION; LIVE-BIRTH-RATES; EJACULATED SPERM; PREGNANCY RATES; DAMAGE; SPERMATOZOA; ICSI; CHROMATIN; IVF; INFERTILITY;
D O I：
10.23736/S0031-0808.23.04870-X
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
The body of evidence supports the negative impact of increased sperm DNA fragmentation (SDF) on natural fertility as well as assisted repro- duction conditions. High SDF has been correlated with low pregnancy and delivery rates following intrauterine insemination. Also, high SDF is accused of reducing the rates of fertilization, implantation, pregnancy, and live birth following in-vitro fertilization (IVF). Despite no impact of high SDF on fertilization or pregnancy rates following intracytoplasmic sperm injection (ICSI), it has been correlated with poor embryo quality and a higher risk of miscarriage. Several methods have been introduced to help select sperm with the best DNA quality to be used in assisted reproductive technology procedures. These include magnetic-activated cell sorting, intracytoplasmic morphologically selected sperm injection, physiologic ICSI, and microfluidic sperm sorters, among others. This article aimed to discuss the impact of high SDF in infertile men on the reproductive outcome of couples undergoing IVF/ICSI. Additionally, this review highlights the principles, advantages, and limitations of differ- ent techniques that are currently used for the selection of sperm with intact DNA to be utilized for ICSI.
引用
收藏
页码：148 / 158
页数：11
相关论文
共 50 条
  • [41] Intracytoplasmic sperm injection
    Graham, F
    Fisher, R
    Peck, J
    NEW ZEALAND MEDICAL JOURNAL, 1996, 109 (1029) : 345 - 345
  • [42] Intracytoplasmic sperm injection
    Van Steirteghem, A
    Devroey, P
    Liebaers, I
    MOLECULAR AND CELLULAR ENDOCRINOLOGY, 2002, 186 (02) : 199 - 203
  • [43] Isolating normal sperm by nuclear characteristics with subsequent intracytoplasmic sperm injection does not seem to improve lowered fecundity found with sperm with high DNA fragmentation indices
    Choe, J. K.
    Check, J. H.
    Yuan, W.
    Horwath, D.
    Summers-Chase, D.
    INTERNATIONAL JOURNAL OF ANDROLOGY, 2005, 28 : 97 - 97
  • [44] Sperm chromatin structure assay high DNA stainability sperm as a marker of early miscarriage after intracytoplasmic sperm injection
    Jerre, Elsa
    Bungum, Mona
    Evenson, Donald
    Giwercman, Aleksander
    FERTILITY AND STERILITY, 2019, 112 (01) : 46 - +
  • [45] Isolating normal sperm by nuclear characteristics with subsequent intracytoplasmic sperm injection does not seem to improve lowered fecundity found with sperm with high DNA fragmentation indices
    Choe, JK
    Check, JH
    Yuan, W
    Horwath, D
    Summers-Chase, D
    Proceedings of the 8th International Congress of Andrology, 2005, : 9 - 12
  • [46] Intracytoplasmic sperm injection
    Hawkins, MM
    Barratt, CLR
    SCIENCE, 1999, 286 (5437) : 51 - 52
  • [47] Intracytoplasmic sperm injection
    Van Steirteghem, A
    BAILLIERES CLINICAL OBSTETRICS AND GYNAECOLOGY, 1997, 11 (04): : 725 - 738
  • [48] INTRACYTOPLASMIC SPERM INJECTION
    VANSTEIRTEGHEM, A
    NAGY, Z
    LIU, J
    JORIS, H
    VERHEYEN, G
    SMITZ, J
    TOURNAYE, H
    LIEBAERS, I
    DEVROEY, P
    BAILLIERES CLINICAL OBSTETRICS AND GYNAECOLOGY, 1994, 8 (01): : 85 - 93
  • [49] Intracytoplasmic sperm injection
    Olivennes, F
    LimaFerreira, A
    Bergere, M
    Hazout, A
    Fanchin, R
    Selva, J
    Frydman, R
    PRESSE MEDICALE, 1996, 25 (33): : 1599 - 1603
  • [50] Intracytoplasmic sperm injection
    De Vos, A
    Van Steirteghem, A
    NEW INSIGHTS IN GYNECOLOGY & OBSTETRICS: RESEARCH AND PRACTICE, 1998, : 89 - 96
12345