Production of 11C, 13N and 15O in proton-induced nuclear reactions up to 200 MeV

被引：6
|
作者：
Rodriguez-Gonzalez, T. [1 ,2 ]
Guerrero, C. [1 ,2 ]
Baecker, C. M. [3 ,4 ,5 ,6 ]
Bauer, J.
Baeumer, C. [4 ,5 ,6 ,8 ]
Brons, S. [7 ]
Jentzen, W. [5 ,6 ,10 ]
Jimenez-Ramos, M. C. [2 ,11 ]
Millan-Callado, M. A. [1 ,2 ]
Schoemers, C. [7 ]
Timmermann, B. [4 ,5 ,6 ,9 ,12 ]
Quesada, J. M. [1 ]
Capote, R. [13 ]
机构：
[1] Univ Seville, Dept Fis Atom Mol & Nucl, Avda Reina Mercedes S-N, Seville 41012, Spain
[2] Univ Sevilla Junta Andalucia CSIC, Ctr Nacl Aceleradores, C-Thomas Alva Edison 7, Seville 41092, Spain
[3] TU Dortmund Univ, Dept Phys, Otto Hahn Str 4a, D-44227 Dortmund, Germany
[4] West German Proton Therapy Ctr Essen, Hufelandstr 55, D-45147 Essen, Germany
[5] West German Canc Ctr, Hufelandstr 55, D-45147 Essen, Germany
[6] Univ Hosp Essen, Hufelandstr 55, D-45147 Essen, Germany
[7] Heidelberg Univ Hosp, Heidelberg Ion Beam Therapy Ctr HIT, Dept Radiat Oncol, Heidelberg, Germany
[8] TU Dortmund Univ, Fac Phys, Otto Hahn Str 4a, D-44227 Dortmund, Germany
[9] German Canc Consortium DKTK, Heidelberg, Germany
[10] Univ Hosp Essen, Clin Nucl Med, Hufelandstr 55, D-45147 Essen, Germany
[11] Univ Seville, Dept Fis Aplicada 2, Avda Reina Mercedes 2, Seville 41092, Spain
[12] Univ Hosp Essen, Dept Particle Therapy, Hufelandstr 55, D-45147 Essen, Germany
[13] IAEA, NAPC Nucl Data Sect, A-1400 Vienna, Austria
来源：
NUCLEAR DATA SHEETS | 2023年 / 187卷
关键词：
ACTIVATION CROSS-SECTIONS; PAR DES PROTONS; POSITRON EMITTERS; THERAPY; CARBON; BEAM; DOSIMETRY; RADIATION; ENERGIES; INDUITES;
D O I：
10.1016/j.nds.2023.01.004
中图分类号：
O57 [原子核物理学、高能物理学];
学科分类号：
070202 ;
摘要：
Production cross sections of light positron emitters 11C (t1/2=20.36 min), 13N (t1/2=9.97 min) and 15O (t1/2=122 s) have been measured for proton-induced reactions on the main relevant constituents of the human body (C, N and O) from threshold up to 200 MeV of proton incident energy. This has been accomplished by means of two complementary experiments at the clinical proton treatment centers WPE (Essen) and HIT (Heidelberg), both in Germany. In the first case, the multi-foil activation technique was combined with PET imaging, a methodology previously developed at CNA (Seville, Spain). In the second experiment, aimed at energies below 50 MeV, the activation of single foils was measured with conventional LaBr3 detectors. In both cases the IAEA monitor reaction natCu(p,x)63Zn data was used for validation purposes. The most complete and accurate set of excitation functions for the production of light-positron emitters 11C, 13N and 15O in proton induced reactions on human tissue up to 200 MeV is presented. These data are needed for nuclear reaction model development and are extremely important to improve the accuracy of the PET range verification in proton radiotherapy. Seven excitation functions have been measured: 12C(p,x)11C, 14N(p,x)11C, 14N(p,x)13N, 14N(p,gamma )15O, 16O(p,x)11C, 16O(p,x)13N and 16O(p,x)15O up to 200 MeV of proton incident energy.
引用
收藏
页码：579 / 596
页数：18
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