Study on antioxidant activity of wheat bran extract microcapsules in vitro and in vivo

Wheat bran extracts (WBE, mainly composed of feruloyl oligosaccharides (FOs)) have been approved by FDA in GRAS Notice. WBE was utilised in octenyl succinate anhydride-modified starch (OSA-starch)-based microcapsules as wall materials to protect beta-carotene (BC) from oxygen. The storage retention and antioxidant indexes in vivo and in vitro of microcapsules were determined. The results showed that these characteristics were positively related to the proportion of WBE in the wall material. The in vivo antioxidant indexes in mouse serum and liver were positively regulated at gavage dose around content in wheat grain (normal dose), while at a higher dosage, the in vivo free oxidative stress fell into disorder. The results indicated that WBE was a good component of wall material, which can improve the antioxidant environment during both storage and consumption. This experiment provides a theoretical basis for the industrial application of WBE in the field of microcapsules.