Molecular genotyping in medullary thyroid cancer

被引：2
|
作者：
Newbold, Kate [1 ,2 ]
机构：
[1] Royal Marsden NHS Fdn Trust Hosp, London, England
[2] Royal Marsden NHS Fdn Trust Hosp, Consultant Clin Oncologist, Fulham Rd, London SW3 6JJ, England
来源：
CURRENT OPINION IN ONCOLOGY | 2023年 / 35卷 / 01期
关键词：
medullary thyroid cancer; rearranged during transfection; ACQUIRED-RESISTANCE; RET PROTOONCOGENE; RAS MUTATIONS; CARCINOMA; ACTIVATION; SELPERCATINIB; CABOZANTINIB;
D O I：
10.1097/CCO.0000000000000915
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
Purpose of reviewThere has been a significant advance in our understanding of the molecular biology of medullary thyroid cancer (MTC) alongside progress in the development of targeted therapies including multikinase and specific rearranged during transfection inhibitors.Recent findingsThis review will examine the latest data investigating the impact of the genomics of MTC on the prediction of the natural history of an individual's disease and the determination, selection and timing of treatment interventions.Recent advances in genotyping in MTC and the development of targeted therapies have impacted on the clinical management of both sporadic and hereditary MTC.
引用
收藏
页码：10 / 14
页数：5
相关论文
共 50 条
  • [21] Management of medullary thyroid cancer
    Ball, D. W.
    MINERVA ENDOCRINOLOGICA, 2011, 36 (01) : 87 - 98
  • [22] Medullary thyroid cancer: an introduction
    Gupta, M. K.
    CURRENT ONCOLOGY, 2019, 26 (05) : 294 - 294
  • [23] Management of Medullary Thyroid Cancer
    Viola, David
    Elisei, Rossella
    ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA, 2019, 48 (01) : 285 - +
  • [24] Hereditary medullary thyroid cancer
    Fendrich, V.
    Zahn, A.
    CHIRURGIE, 2023, 94 (05): : 393 - 399
  • [25] MEDULLARY-THYROID CANCER
    CALMETTES, C
    M S-MEDECINE SCIENCES, 1991, 7 (01): : 22 - 29
  • [26] VandetanibIn Medullary Thyroid Cancer
    James E. Frampton
    Drugs, 2012, 72 : 1423 - 1436
  • [27] Medullary thyroid cancer.
    Kebebew E.
    Clark O.H.
    Current Treatment Options in Oncology, 2000, 1 (4) : 359 - 367
  • [28] THYROID MEDULLARY CANCER IMAGING
    BAULIEU, JL
    GUILLOTEAU, D
    BAULIEU, F
    BESNARD, JC
    POURCELOT, L
    BULLETIN DU CANCER, 1984, 71 (03) : 182 - 187
  • [29] MEDULLARY CANCER OF THE THYROID - PHYSIOPATHOLOGY
    MILHAUD, G
    ANNALES DE MEDECINE INTERNE, 1984, 135 (05): : 332 - 334
  • [30] Cystic medullary thyroid cancer
    Liberatore, E
    Emmolo, I
    SURGERY, 1996, 120 (05) : 903 - 903
12345