Disulfiram-like Reaction With Ginaton: A Case Report and Literature Review

被引:2
|
作者
Dang, Xiangji [1 ]
Wang, Rui [1 ]
Liu, Yan [2 ,3 ]
机构
[1] Lanzhou Univ, Dept Rheumatol, Hosp 2, Lanzhou, Peoples R China
[2] Lanzhou Univ, Sch Pharm, Lanzhou, Peoples R China
[3] Lanzhou Univ, Sch Pharm, Donggang West Rd 199, Lanzhou 730020, Peoples R China
关键词
Arrhythmia; Alcohol; Disulfiram-like reaction; Ginaton (extraction of Ginkgo biloba ); TOXICITY;
D O I
10.1016/j.clinthera.2023.08.013
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Alcohol consumption, even minimal, can exacerbate the disulfiram-like reaction (also referred to as acetaldehyde syndrome) that occurs with the use of medications that impede the breakdown of acetaldehyde. Such medications include Ginaton, a proprietary tablet formulation of Ginkgo biloba extract commonly used in Europe, Asia, and the United States for cardiovascular and nervous system health. This article details such a case from China. Healthcare providers should be proactive in educating patients about the potential adverse reactions related to using Ginaton and the importance of avoiding alcohol consumption while using it. Patients should also be advised to disclose their alcohol-consumption habits and seek medical advice before initiating treatment with any medication or supplement during treatment with Ginaton.
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页码:1151 / 1154
页数:4
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