Radiographic, MRI, and CT findings in a young dog with Becker-like muscular dystrophy

被引:2
|
作者
Costanzo, Giulia [1 ,4 ]
Minei, Sergio [1 ]
Zini, Eric [1 ,2 ,3 ]
Gracis, Margherita [1 ]
Lacava, Giuseppe [1 ]
机构
[1] AniCura Ist Vet Novara, Granozzo con Monticello N, Novara, Italy
[2] Univ Zurich, Vetsuisse Fac, Clin Small Anim Internal Med, Zurich, Switzerland
[3] Univ Padua, Dept Anim Med Prod & Hlth, Legnaro, Italy
[4] AniCura Ist Vet Novara, Diagnost Imaging Dept, Str Prov 9, I-28060 Granozzocon Monticello NO, Italy
关键词
Canine; dystrophin; gene; masticatory myopathy; muscular biopsy; JAPANESE SPITZ;
D O I
10.1111/vru.13200
中图分类号
S85 [动物医学(兽医学)];
学科分类号
0906 ;
摘要
An 8-month-old, male, crossbreed dog was presented for macroglossia, reduced mandibular extension, ptyalism, dysphagia, and regurgitation. Serum creatine kinase and aspartate aminotransferase activity were markedly increased. Thoracic radiographs showed an axial gastro-esophageal hiatal hernia, diaphragmatic thickening, and asymmetry. Magnetic resonance imaging of the head showed a severely enlarged tongue, symmetric increase in size of the geniohyoid and mylohyoid muscles, and diffuse masticatory hypomyotrophy. Whole-body CT ruled out other musculoskeletal abnormalities and further characterized the radiographic and MRI findings. Muscular histopathology was consistent with Becker muscular dystrophy.
引用
收藏
页码:E19 / E22
页数:4
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