A Comprehensive Review of Herbal Medicines for the Treatment of Alzheimer's Disease

被引:1
|
作者
Shadab, Sumbul [1 ]
Rao, G. S. N. Koteswara [1 ,2 ]
Paliwal, Deepika [1 ]
Yadav, Devdhar [1 ]
Alam, Aftab [1 ]
Singh, Amit [1 ]
Sultana, Md Jaha [3 ]
机构
[1] Galgotias Univ, Sch Med & Allied Sci, Dept Pharm, Greater Noida, Uttar Pradesh, India
[2] SVKMS NMIMS, Shobhaben Pratapbhai Patel Sch Pharm & Technol Man, VL Mehta Rd,Vile Parle W, Mumbai 400056, India
[3] Koneru Lakshmaiah Educ Fdn, K L Coll Pharm, Vaddeswaram, Andhra Prades, India
关键词
Alzheimer's disease; cerebral blood flow; memory; medicinal plants; active component; seniles plaque; MODERATE ALZHEIMERS-DISEASE; DERIVATIVE 2-(4 BENZYLOXYPHENYL)-3-HYDROXY-CHROMEN-4-ONE; CHOLINESTERASE INHIBITORY-ACTIVITY; SALVIA-OFFICINALIS L; CORIANDRUM-SATIVUM L; KOREAN RED GINSENG; GINKGO-BILOBA; DOUBLE-BLIND; MOUSE MODEL; COGNITIVE PERFORMANCE;
D O I
10.2174/2215083810666230608151821
中图分类号
R [医药、卫生];
学科分类号
10 ;
摘要
The choices of treatment for Alzheimer's are based on NMDA-receptor antagonists and cholinesterase inhibitors, although their efficacy as a therapy is still up for debate. BPSD (Behavioural and Psychological Symptoms of Dementia) have been treated using herbal medicine products, with varying degrees of success. This manuscript sets out to answer the question, "Can herbs be effective in the treatment of cognitive impairments in patients?" by examining evidences from controlled research. The process by which Alzheimer's disease develops remains a mystery, and the present Alzheimer's treatment strategy, which consists of administering a single medicine to treat a single target, appears to be clinically ineffective. AD treatment will require a combination of approaches that target many signs and causes of the disease. The results of currently available licensed therapies for AD are often disappointing, and alternative medicine, especially herbal therapy, may play a role. Over 80% of the world's population, particularly in developing nation, gets their main health care from herbal medicines. They have persisted through the years due to their low risk, high reward, widespread acceptance across cultures, and absence of detrimental side effects. In some cases, herbal remedies have proven to be more effective than conventional medical treatments. They are assumed to be natural unless proven otherwise by the presence of unnatural additives. The absence of adverse reactions is a major advantage of herbal treatment. In addition, they provide ongoing advantages to health. Salvia officinalis, Ginkgo biloba, Melissa officinalis, Panax ginseng, Coriandrum sativum, Curcuma longa, Ashwagandha, Uncaria Tomentosa, Crocus Sativus and Allium Sativum are all studied for their potential effects on Alzheimer's disease.
引用
收藏
页码:98 / 116
页数:19
相关论文
共 50 条
  • [31] The use of herbal medicine in Alzheimer's disease - A systematic review
    dos Santos-Neto, Leopoldo Luiz
    de Vilhena Toledo, Maria Alice
    Medeiros-Souza, Patricia
    de Souza, Gustavo Almeida
    EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE, 2006, 3 (04) : 441 - 445
  • [32] A comprehensive review on phytosomes as a novel dosage form for herbal medicines
    Alam, Shadab
    Khan, Mohammad Irfan
    Rizvi, Aleza
    Badruddeen
    Akhtar, Juber
    Ahmad, Mohammad
    Ul Hasan, Rizwan
    ANNALS OF PHYTOMEDICINE-AN INTERNATIONAL JOURNAL, 2023, 12 (02): : 254 - 265
  • [33] Herbal medicines for the management of irritable bowel syndrome: A comprehensive review
    Rahimi, Roja
    Abdollahi, Mohammad
    WORLD JOURNAL OF GASTROENTEROLOGY, 2012, 18 (07) : 589 - 600
  • [34] Nanoparticles loaded with natural medicines for the treatment of Alzheimer's disease
    Liu, Nanyang
    Ruan, Juanjuan
    Li, Hao
    Fu, Jianhua
    FRONTIERS IN NEUROSCIENCE, 2023, 17
  • [35] Herbal therapy: a new pathway for the treatment of Alzheimer's disease
    Jinzhou Tian
    Jing Shi
    Xuekai Zhang
    Yongyan Wang
    Alzheimer's Research & Therapy, 2
  • [36] Herbal therapy: a new pathway for the treatment of Alzheimer's disease
    Tian, Jinzhou
    Shi, Jing
    Zhang, Xuekai
    Wang, Yongyan
    ALZHEIMERS RESEARCH & THERAPY, 2010, 2 (05):
  • [37] Pharmacological Effects of Active Components of Chinese Herbal Medicine in the Treatment of Alzheimer's Disease: A Review
    Wang, Zhi-Yong
    Liu, Jian-Gang
    Li, Hao
    Yang, Hui-Ming
    AMERICAN JOURNAL OF CHINESE MEDICINE, 2016, 44 (08): : 1525 - 1541
  • [38] Herbal Approaches for Alzheimer Disease: A Review
    Yoggeta
    Bhatia, Deepika
    Bhatti, Manisha
    JOURNAL OF PHARMACEUTICAL RESEARCH INTERNATIONAL, 2021, 33 (53B) : 311 - 324
  • [39] Efficacy and safety of herbal medicines for idiopathic Parkinson's disease: A systematic review
    Chung, Vincent
    Liu, Liang
    Bian, Zhaoxiang
    Zhao, Zhongzhen
    Fong, Wai Leuk
    Kum, Wan Fung
    Gao, Jing
    Li, Min
    MOVEMENT DISORDERS, 2006, 21 (10) : 1709 - 1715
  • [40] Behavioural genetics of Alzheimer's disease: a comprehensive review
    Flirski, Marcin
    Sobow, Tomasz
    Kloszewska, Iwona
    ARCHIVES OF MEDICAL SCIENCE, 2011, 7 (02) : 195 - 210