Cryptosporidium secretome sheds new light on host-parasite interactions

被引：1

作者：

Coppens, Isabelle ^{[1
]}

Ward, Honorine D. ^{[2
]}

机构：

[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD USA

[2] Tufts Med Ctr, Div Geog Med & Infect Dis, Boston, MA 02111 USA

来源：

TRENDS IN PARASITOLOGY | 2023年 / 39卷 / 07期

基金：

美国国家卫生研究院;

关键词：

TARGETS;

D O I：

10.1016/j.pt.2023.04.008

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Invasive Cryptosporidium sporozoites contain organelles that secrete unique proteins to facilitate invasion and remodeling of the infected cell. By identifying a novel secretory organelle, 'small granules', and defining the global content of all the secretory organelles, Guerin et al. set the stage to uncover molecular determinants of virulence at the host cell interface.

引用

页码：499 / 500

页数：2

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