Cryptosporidium secretome sheds new light on host-parasite interactions

被引:1
|
作者
Coppens, Isabelle [1 ]
Ward, Honorine D. [2 ]
机构
[1] Johns Hopkins Bloomberg Sch Publ Hlth, Dept Mol Microbiol & Immunol, Baltimore, MD USA
[2] Tufts Med Ctr, Div Geog Med & Infect Dis, Boston, MA 02111 USA
基金
美国国家卫生研究院;
关键词
TARGETS;
D O I
10.1016/j.pt.2023.04.008
中图分类号
R38 [医学寄生虫学]; Q [生物科学];
学科分类号
07 ; 0710 ; 09 ; 100103 ;
摘要
Invasive Cryptosporidium sporozoites contain organelles that secrete unique proteins to facilitate invasion and remodeling of the infected cell. By identifying a novel secretory organelle, 'small granules', and defining the global content of all the secretory organelles, Guerin et al. set the stage to uncover molecular determinants of virulence at the host cell interface.
引用
收藏
页码:499 / 500
页数:2
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