Phytosteroids from Roots of Psammosilene tunicoides WCWu et CYWu

被引：0
|
作者：
Wang, Ziliang [1 ]
Li, Hongrui [1 ]
Li, Yuxiao [1 ,2 ]
Nie, Kexin [1 ]
Yang, Xiuxia [1 ]
Bai, Xishan [1 ]
Li, Yanhong [1 ]
Huang, Xiangzhong [1 ]
机构：
[1] Yunnan Minzu Univ, Key Lab Chem Ethn Med Resources, State Ethn Affairs Commiss & Minist Educ, Kunming 650504, Yunnan, Peoples R China
[2] Yunnan Plateau Thermal Hlth Ind Innovat Res Inst, Tengchong 679100, Yunnan, Peoples R China
来源：
RECORDS OF NATURAL PRODUCTS | 2024年 / 18卷 / 02期
基金：
中国国家自然科学基金;
关键词：
Psammosilene tunicoides; phytoecdysteroid; nitric oxide inhibition activity; RAW; 264.7; cells;
D O I：
10.25135/rnp.444.2312.2991
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
To explore structurally and pharmacologically interesting secondary metabolites from Psammosilene tunicoides, a crude extract of this plant was investigated, leading to the isolation of a new phytoecdysteroid, furoecdysterone (1) and four known phytosteroid compounds, ecdysterone (2), 22-deoxyecdysterone (3), beta-sitosteryl D-glucoside (4), and beta-sitosterol (5). Their structures were identified based on a detailed analysis of NMR spectra and MS data. Those compounds, except for 2, showed moderate NO inhibition activities on lipopolysaccharide (LPS)-induced release in RAW 264.7 cells.
引用
收藏
页码：290 / 295
页数：6
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