Incidence rates of childhood asthma with recurrent exacerbations in the US Environmental influences on Child Health Outcomes (ECHO) program

被引：4

作者：

Miller, Rachel L. ^{[1
]}

Schuh, Holly ^{[3
]}

Chandran, Aruna ^{[3
]}

Aris, Izzuddin M. ^{[4
,5
]}

Bendixsen, Casper ^{[10
]}

Blossom, Jeffrey ^{[11
]}

Breton, Carrie ^{[12
]}

Camargo Jr, Carlos A. ^{[6
,7
]}

Canino, Glorisa ^{[13
]}

Carroll, Kecia N. ^{[1
]}

Commodore, Sarah ^{[14
]}

Cordero, Jose F. ^{[15
]}

Dabelea, Dana M. ^{[16
]}

Ferrara, Assiamira ^{[18
]}

Fry, Rebecca C. ^{[19
]}

Ganiban, Jody M. ^{[20
]}

Gern, James E. ^{[21
]}

Gilliland, Frank D. ^{[12
]}

Gold, Diane R. ^{[8
,9
]}

Habre, Rima ^{[12
]}

Hare, Marion E. ^{[22
]}

Harte, Robyn N. ^{[17
]}

Hartert, Tina ^{[23
]}

Hasegawa, Kohei ^{[7
]}

Hershey, Gurjit K. Khurana ^{[24
,25
]}

Jackson, Daniel J.

Joseph, Christine ^{[26
]}

Kerver, Jean M. ^{[27
]}

Kim, Haejin ^{[26
]}

Litonjua, Augusto A. ^{[28
]}

Marsit, Carmen J. ^{[30
]}

McEvoy, Cindy ^{[31
]}

Mendonca, Eneida A. ^{[24
,25
]}

Moore, Paul E.

Nkoy, Flory L. ^{[32
]}

O'Connor, Thomas G. ^{[29
]}

Oken, Emily ^{[4
,5
]}

Ownby, Dennis ^{[26
]}

Perzanowski, Matthew ^{[2
]}

Rivera-Spoljaric, Katherine ^{[33
]}

Ryan, Patrick H. ^{[24
,25
]}

Singh, Anne Marie

Stanford, Joseph B. ^{[32
]}

Wright, Rosalind J. ^{[1
]}

Wright, Robert O. ^{[1
]}

Zanobetti, Antonella ^{[9
]}

Zoratti, Edward ^{[26
]}

Johnson, Christine C. ^{[26
]}

机构：

[1] Icahn Sch Med Mt Sinai, New York, NY USA

[2] Columbia Univ, Mailman Sch Publ Hlth, New York, NY USA

[3] Johns Hopkins Univ, Bloomberg Sch Publ Hlth, Dept Epidemiol, Baltimore, MD USA

[4] Harvard Med Sch, Dept Populat Med, Boston, MA USA

[5] Harvard Pilgrim Hlth Care Inc, Boston, MA USA

[6] Harvard Med Sch, Dept Epidemiol, Boston, MA USA

[7] Harvard Med Sch, Massachusetts Gen Hosp, Dept Emergency Med, Boston, MA USA

[8] Harvard Med Sch, Brigham & Womens Hosp, Boston, MA USA

[9] Harvard TH Chan Sch Publ Hlth, Dept Environm Hlth, Boston, MA USA

[10] Marshfield Clin Res Inst, Marshfield, WI USA

[11] Harvard Univ, Ctr Geog Anal, Cambridge, MA USA

[12] Univ Southern Calif, Keck Sch Med, Los Angeles, CA USA

[13] Univ Puerto Rico, Behav Sci Res Inst, San Juan, PR USA

[14] Med Univ South Carolina, Charleston, SC USA

[15] Univ Georgia, Coll Publ Hlth, Athens, GA USA

[16] Univ Colorado Anschutz Med Campus, Aurora, CO USA

[17] Colorado Sch Publ Hlth, Aurora, CO USA

[18] Kaiser Permanente Northern Calif, Div Res, Oakland, CA USA

[19] Univ North Carolina Chapel Hill, Gillings Sch Global Publ Hlth, Chapel Hill, NC USA

[20] George Washington Univ, Washington, DC USA

[21] Univ Wisconsin, Sch Med & Publ Heath, Madison, WI USA

[22] Univ Tennessee, Hlth Sci Ctr, Memphis, TN USA

[23] Vanderbilt Univ, Sch Med, Nashville, TN USA

[24] Univ Cincinnati, Cincinnati, OH USA

[25] Cincinnati Childrens Hosp Med Ctr, Cincinnati, OH USA

[26] Henry Ford Hlth, Detroit, MI USA

[27] Michigan State Univ, Coll Human Med, Dept Epidemiol & Biostat, E Lansing, MI USA

[28] Golisano Childrens Hosp, Dept Pediat, Div Pediat Pulm Med, Rochester, NY USA

[29] Univ Rochester, Med Ctr, Sch Med & Dent, Rochester, NY USA

[30] Emory Univ, Rollins Sch Publ Hlth, Atlanta, GA USA

[31] Oregon Hlth & Sci Univ, Portland, OR USA

[32] Univ Utah Hlth, Salt Lake City, UT USA

[33] Washington Univ, St Louis Childrens Hosp, St Louis, MO USA

来源：

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY | 2023年 / 152卷 / 01期

基金：

美国国家卫生研究院;

关键词：

Asthma; recurrent exacerbations; incidence rates; environmental and social determinants of asthma; UNITED-STATES; RISK-FACTORS; PHENOTYPES; AGE;

D O I：

10.1016/j.jaci.2023.03.016

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Background: Descriptive epidemiological data on incidence rates (IRs) of asthma with recurrent exacerbations (ARE) are sparse. Objectives: This study hypothesized that IRs for ARE would vary by time, geography, age, and race and ethnicity, irrespective of parental asthma history. Methods: The investigators leveraged data from 17,246 children born after 1990 enrolled in 59 US with 1 Puerto Rican cohort in the Environmental Influences on Child Health Outcomes (ECHO) consortium to estimate IRs for ARE. Results: The overall crude IR for ARE was 6.07 per 1000 person-years (95% CI: 5.63-6.51) and was highest for children aged 2-4 years, for Hispanic Black and non-Hispanic Black children, and for those with a parental history of asthma. ARE IRs were higher for 2-to 4-year-olds in each race and ethnicity category and for both sexes. Multivariable analysis confirmed higher adjusted ARE IRs (aIRRs) for children born 2000-2009 compared with those born 1990-1999 and 2010-2017, 2-4 versus 10-19 years old (aIRR = 15.36; 95% CI: 12.09-19.52), and for males versus females (aIRR = 1.34; 95% CI 1.16-1.55). Black children (non-Hispanic and Hispanic) had higher rates than non-Hispanic White children (aIRR = 2.51; 95% CI 2.10-2.99; and aIRR = 2.04; 95% CI: 1.22-3.39, respectively). Children born in the Midwest, Northeast and South had higher rates than those born in the West (P < .01 for each comparison). Children with a parental history of asthma had rates nearly 3 times higher than those without such history (aIRR = 2.90; 95% CI: 2.43-3.46). Conclusions: Factors associated with time, geography, age, race and ethnicity, sex, and parental history appear to influence the inception of ARE among children and adolescents. (J Allergy Clin Immunol 2023;152:84-93.)

引用

页码：84 / 93

页数：10

共 50 条

[31] Greater Gestational Vitamin D Status is Associated with Reduced Childhood Behavioral Problems in the Environmental Influences on Child Health Outcomes Program
Melough, Melissa M.
Li, Mingyi
Hamra, Ghassan
Palmore, Meredith
Sauder, Katherine A.
Dunlop, Anne L.
Lewinn, Kaja Z.
Zhao, Qi
Kelly, Rachel S.
Switkowski, Karen M.
Hipwell, Alison E.
Korrick, Susan A.
Collett, Brent R.
Mackenzie, Debra
Nozadi, Sara S.
Kerver, Jean M.
Schmidt, Rebecca J.
Mcgrath, Monica
[J]. JOURNAL OF NUTRITION, 2023, 153 (05): : 1502 - 1511
[32] Association of Gestational Diabetes Mellitus and Perinatal Maternal Depression with early childhood behavioral problems: An Environmental Influences on Child Health Outcomes (ECHO) Study
Shuffrey, Lauren C.
Morales, Santiago
Jacobson, Melanie H.
Enlow, Michelle Bosquet
Ghassabian, Akhgar
Margolis, Amy E.
Lucchini, Maristella
Carroll, Kecia N.
Crum, Rosa M.
Dabelea, Dana
Deutsch, Arielle
Fifer, William P.
Goldson, Brandon
Hockett, Christine W.
Mason, W. Alex
Jacobson, Lisette T.
O'Connor, Thomas G.
Pini, Nicolo
Rayport, Yael
Sania, Ayesha
Trasande, Leonardo
Wright, Rosalind J.
Lee, Seonjoo
Monk, Catherine
[J]. CHILD DEVELOPMENT, 2023, 94 (06) : 1595 - 1609
[33] SLEEP DISPARITIES BY RACE/ETHNICITY DURING PREGNANCY: AN ENVIRONMENTAL INFLUENCES ON CHILD HEALTH OUTCOMES (ECHO) STUDY
Lucchini, Maristella
O'Brien, Louise
Kahn, Linda
Brennan, Patricia
Baron, Kelly
Knapp, Emily
Lugo, Claudia
Shuffrey, Lauren
Dunietz, Galit
Zhu, Yeyi
Alcantara, Carmela
Fifer, William
Elliott, Amy
[J]. SLEEP, 2022, 45 : A28 - A28
[34] Associations between COVID-19-related family hardships/distress and children's Adverse Childhood Experiences during the pandemic: The Environmental influences on Child Health Outcomes (ECHO) program
Thierry, Karen L.
Hockett, Christine W.
Elliott, Amy J.
Wosu, Adaeze C.
Chandran, Aruna
Blackwell, Courtney K.
Margolis, Amy E.
Karagas, Margaret R.
Vega, Carmen Velez
Duarte, Cristiane S.
Camargo Jr, Carlos A.
Lester, Barry M.
Mcgowan, Elisabeth C.
Ferrara, Assiamira
O'Connor, Thomas G.
Mcevoy, Cindy T.
Hipwell, Alison E.
Leve, Leslie D.
Ganiban, Jody M.
Comstock, Sarah S.
Dabelea, Dana
[J]. CHILD ABUSE & NEGLECT, 2023, 146
[35] Independent and joint effects of neighborhood-level environmental and socioeconomic exposures on body mass index in early childhood: The environmental influences on child health outcomes (ECHO) cohort
Martenies, Sheena E.
Oloo, Alice
Magzamen, Sheryl
Ji, Nan
Khalili, Roxana
Kaur, Simrandeep
Xu, Yan
Yang, Tingyu
Bastain, Theresa M.
Breton, Carrie, V
Farzan, Shohreh F.
Habre, Rima
Dabelea, Dana
[J]. ENVIRONMENTAL RESEARCH, 2024, 253
[36] Public drinking water contaminant estimates for birth cohorts in the Environmental Influences on Child Health Outcomes (ECHO) Cohort
Bloomquist, Tessa R.
Spaur, Maya
Cerna-Turoff, Ilan
Kress, Amii M.
Burjak, Mohamad
Kupsco, Allison
Casey, Joan A.
Herbstman, Julie B.
Nigra, Anne E.
[J]. JOURNAL OF EXPOSURE SCIENCE AND ENVIRONMENTAL EPIDEMIOLOGY, 2024,
[37] Associations of Organophosphate Ester Flame Retardant Exposures during Pregnancy with Gestational Duration and Fetal Growth: The Environmental influences on Child Health Outcomes (ECHO) Program
Oh, Jiwon
Buckley, Jessie P.
Li, Xuan
Gachigi, Kennedy K.
Kannan, Kurunthachalam
Lyu, Wenjie
Ames, Jennifer L.
Barrett, Emily S.
Bastain, Theresa M.
Breton, Carrie, V
Buss, Claudia
Croen, Lisa A.
Dunlop, Anne L.
Ferrara, Assiamira
Ghassabian, Akhgar
Herbstman, Julie B.
Hernandez-Castro, Ixel
Hertz-Picciotto, Irva
Kahn, Linda G.
Karagas, Margaret R.
Kuiper, Jordan R.
McEvoy, Cindy T.
Meeker, John D.
Morello-Frosch, Rachel
Padula, Amy M.
Romano, Megan E.
Sathyanarayana, Sheela
Schantz, Susan
Schmidt, Rebecca J.
Simhan, Hyagriv
Starling, Anne P.
Tylavsky, Frances A.
Volk, Heather E.
Woodruff, Tracey J.
Zhu, Yeyi
Bennett, Deborah H.
[J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2024, 132 (01)
[38] Growing a New Study Environmental Influences on Child Health Outcomes
Schmidt, Charles W.
[J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 2015, 123 (10) : A260 - A263
[39] Airborne Lead Exposure and Childhood Cognition: The Environmental Influences on Child Health Outcomes (ECHO) Cohort (2003-2022) (vol 114, pg 309, 2024)
Gatzke-Kopp, Lisa M.
Willoughby, Michael
McArthur, Kristen
Wychgram, Cara
Folch, David C.
Brunswasser, Steve
Dabelea, Dana
Elliott, Amy J.
Hartert, Tina
Karagas, Margaret
McEvoy, Cindy T.
VanDerslice, James A.
Wright, Robert O.
Wright, Rosalind J.
Kress, Amii M.
[J]. AMERICAN JOURNAL OF PUBLIC HEALTH, 2024, 114 (07) : 746 - 746
[40] A MULTI-CENTER NATIONAL APPROACH TO STUDYING THE IMPORTANCE OF THE PLACENTA TO MATERNAL-CHILD HEALTH AND ENVIRONMENTAL EXPOSURES: THE NIH ENVIRONMENTAL INFLUENCES ON CHILD HEALTH OUTCOMES (ECHO) STUDY
Miller, Richard K.
[J]. PLACENTA, 2019, 83 : E6 - E6

← 1 2 3 4 5 →