PRECLINICAL TESTING OF THE EFFICACY AND SAFETY OF CRISPR/CAS9 GENE EDITED CAR-T CELL THERAPY FOR DIFFUSE MIDLINE GLIOMA (DMG)

被引：0
|
作者：
Balakrishnan, Ilango [1 ]
Leach, Lillie [1 ]
Pierce, Angela [1 ]
Lakshmanachetty, Senthilnath [1 ]
Madhavan, Krishna [1 ]
Fosmire, Susan [1 ]
Chatwin, Hannah [1 ]
Green, Adam [1 ]
Fry, Terry [1 ]
Vibhakar, Rajeev [1 ]
Kohler, Eric. M. [1 ]
Venkataraman, Sujatha [1 ]
机构：
[1] Univ Colorado, Aurora, CO USA
来源：
NEURO-ONCOLOGY | 2023年 / 25卷
关键词：
D O I：
10.1093/neuonc/noad073.079
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
DIPG-32
引用
收藏
页数：1
相关论文
共 50 条
  • [41] Novel technologies for improving the safety and efficacy of CAR-T cell therapy
    Ohta, Keisuke
    Sakoda, Yukimi
    Tamada, Koji
    INTERNATIONAL JOURNAL OF HEMATOLOGY, 2023, 117 (05) : 647 - 651
  • [42] Gene Knock-in by CRISPR/Cas9 and Cell Sorting in Macrophage and T Cell Lines
    Zhang, Lichen
    Huang, Rong
    Lu, Liaoxun
    Fu, Rui
    Guo, Guo
    Gu, Yanrong
    Liu, Zhuangzhuang
    He, Le
    Malissen, Marie
    Liang, Yinming
    JOVE-JOURNAL OF VISUALIZED EXPERIMENTS, 2021, (177):
  • [43] Megatal, Crispr/Cas9, and Talen T-Cell Receptor Gene Editing
    Osborn, Mark J.
    Webber, Beau R.
    Knipping, Friederike
    Lonetree, Cara-lin
    DeFeo, Anthony
    McElroy, Amber
    Starker, Colby
    Gabriel, Richard
    Merkel, Sarah
    Hippen, Keli L.
    Voytas, Daniel
    von Kalle, Christof
    Schmidt, Manfred
    Miller, Jeffrey S.
    Jarjour, Jordan
    Astrakhan, Alexander
    Scharenberg, Andrew M.
    Tolar, Jakub
    Blazar, Bruce R.
    BLOOD, 2015, 126 (23)
  • [44] Safety of CAR-T Cell Therapy in Asymptomatic Patients with Positive Respiratory Viral Testing Prior to CAR-T Infusions
    Muenzen, Reid M.
    Chong, Emeline R.
    Therwhanger, Dylan
    Landsburg, Daniel J.
    Nasta, Sunita D.
    Svoboda, Jakub
    Barta, Stefan K.
    Hughes, Mitchell E.
    Weber, Elizabeth
    Ruella, Marco
    Frey, Noelle V.
    Porter, David L.
    Schuster, Stephen J.
    Chong, Elise A.
    BLOOD, 2023, 142
  • [45] CRISPR/Cas9 revitalizes adoptive T-cell therapy for cancer immunotherapy
    Ghaffari, Sasan
    Khalili, Nastaran
    Rezaei, Nima
    JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2021, 40 (01)
  • [46] CRISPR/Cas9 revitalizes adoptive T-cell therapy for cancer immunotherapy
    Sasan Ghaffari
    Nastaran Khalili
    Nima Rezaei
    Journal of Experimental & Clinical Cancer Research, 40
  • [47] Preclinical Safety and Feasibility Study of a CRISPR/Cas9 Gene Editing Platform to Treat Wiskott Aldrich Syndrome
    Naseem, Asma
    Rai, Rajeev
    Turchiano, Giandomenico
    Whittaker, Thomas
    Thrasher, Adrian J.
    Cavazza, Alessia
    MOLECULAR THERAPY, 2022, 30 (04) : 34 - 34
  • [48] MRNA CAR T CELL TRAFFICKING FOLLOWING INTRA-VENTRICULAR ADMINISTRATION IN PRECLINICAL MODELS OF DIFFUSE MIDLINE GLIOMA
    Al-atrache, Zein
    Mcmanus, Olivia
    Harvey, Kyra
    Dickson, Conor
    Patterson, Luke
    Beaubien, Ezra
    Wilson, Cullen
    Hajeebu, Sreehita
    Keil, Samantha
    Braun, Molly
    Meechan, Michael
    Vitanza, Nicholas
    Iliff, Jeffrey
    Madsen, Peter
    Foster, Jessica
    NEURO-ONCOLOGY, 2023, 25
  • [49] Improving Efficacy of CAR T Cells through CRISPR/Cas9 Mediated Knockout of TGFBR2
    Welstead, G. Grant
    Vong, Queenie
    Nye, Chris
    Hause, Ron
    Clouser, Chris
    Jones, Jon
    Burleigh, Stephen
    Borges, Christopher M.
    Chin, Melissa
    Marco, Eugenio
    Da Silva, Jen
    Harbinski, Fred
    Giannoukos, Georgia
    Dhanapal, Vidya
    Jiang, Yue
    Salmon, Ruth
    Wilson, Christopher J.
    Myer, Vic
    Bond, Christopher J.
    Sather, Blythe D.
    MOLECULAR THERAPY, 2018, 26 (05) : 61 - 61
  • [50] CRISPR/Cas9技术在CAR-T细胞治疗肿瘤中作用的研究进展
    伍琦
    王绍波
    基础医学与临床, 2023, 43 (08) : 1313 - 1316
12345