Highly diastereoselective Heck-Matsuda reaction with pyrazolyl diazonium salts

被引：1
|
作者：
Bertozzi, F. [1 ]
Bertozzi, F. [1 ]
Bertozzi, S. M. [2 ]
Bandiera, T. [1 ]
Bertozzi, F. [1 ]
机构：
[1] Fdn Ist Italiano Tecnol, D3-PharmaChemistry, Via Morego 30, I-16163 Genoa, Italy
[2] Fdn Ist Italiano Tecnol, Analyt Chem Facil, Via Morego 30, I-16163 Genoa, Italy
来源：
NEW JOURNAL OF CHEMISTRY | 2023年 / 47卷 / 21期
关键词：
ARYLATION; ARYL;
D O I：
10.1039/d3nj01724a
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The Heck-Matsuda (HM) reaction is a powerful synthetic approach cut out for C-C bonds formation under mild conditions. We demonstrated that pyrazolyl diazonium salts are suitable reagents in this protocol, allowing us to deliver highly substituted cyclopentenols and cyclopentenamines with an excellent degree of diastereoselectivity and a control of enantioselectivity.
引用
收藏
页码：9994 / 9997
页数：4
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