Advances in Self-Assembled Peptides as Drug Carriers

被引:12
|
作者
Gao, Yawen [1 ]
Wang, Lele [1 ]
Zhang, Xue [1 ]
Zhou, Ziling [1 ]
Shen, Xinzhu [1 ]
Hu, Haodong [1 ]
Sun, Rui [1 ]
Tang, Jihui [1 ]
机构
[1] Anhui Med Univ, Anhui Inst Innovat Drugs, Sch Pharm, Inflammat & Immune Mediated Dis Lab Anhui Prov, Hefei 230032, Peoples R China
关键词
peptides; self-assembly; nanostructures; influencing factors; drug carriers; ALPHA-HELIX; NANOTUBES; DELIVERY; HYDROGELS; MICELLES; SOLVENT; DESIGN; NANOMATERIALS; PROTEINS; THERAPY;
D O I
10.3390/pharmaceutics15020482
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
In recent years, self-assembled peptide nanotechnology has attracted a great deal of attention for its ability to form various regular and ordered structures with diverse and practical functions. Self-assembled peptides can exist in different environments and are a kind of medical bio-regenerative material with unique structures. These materials have good biocompatibility and controllability and can form nanoparticles, nanofibers and hydrogels to perform specific morphological functions, which are widely used in biomedical and material science fields. In this paper, the properties of self-assembled peptides, their influencing factors and the nanostructures that they form are reviewed, and the applications of self-assembled peptides as drug carriers are highlighted. Finally, the prospects and challenges for developing self-assembled peptide nanomaterials are briefly discussed.
引用
收藏
页数:20
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