Safety and clinical activity of oleclumab (O) ± durvalumab (D) plus chemotherapy (CT) in patients (pts) with metastatic pancreatic ductal adenocarcinoma (mPDAC): A phase 1b/2 randomized study

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作者
Coveler, Andrew L.
Reilley, Matthew
Zalupski, Mark
Macarulla, Teresa
Fountzilas, Christos
Castanon Alvarez, Eduardo
Nagrial, Adnan
Volodymyrivna Uboha, Nataliya
Frentzas, Sophia
Overman, Michael J.
Noonan, Anne M.
Messersmith, Wells A.
Pavlakis, Nick
Mettu, Niharika B.
Smith, Paul
Murtomaki, Elina
Bragulat, Veronique
Cooper, Zachary A.
Kumar, Rakesh
Spigel, David
机构
[1] Fred Hutchinson Canc Ctr, Seattle, WA USA
[2] Univ Virginia, Ctr Comprehens Canc, Charlottesville, VA USA
[3] Univ Michigan Hlth Syst, Ann Arbor, MI USA
[4] Hosp Univ Vall DHebron, Barcelona, Spain
[5] Roswell Pk Canc Inst, Buffalo, NY USA
[6] Clin Univ Navarra, Madrid, Spain
[7] Blacktown Hosp, Sydney, NSW, Australia
[8] Univ Wisconsin, Carbone Canc Ctr, Madison, WI USA
[9] Monash Hlth Monash Med Ctr, Clayton, Vic, Australia
[10] Univ Texas MD Anderson Canc Ctr, Houston, TX USA
[11] Ohio State Univ, Ctr Comprehens Canc, Columbus, OH USA
[12] Univ Colorado, Denver, CO USA
[13] Royal North Shore Hosp, Northern Sydney Canc Ctr, Sydney, NSW, Australia
[14] Duke Univ, Med Ctr, Durham, NC USA
[15] AstraZeneca, Cambridge, England
[16] AstraZeneca, Gaithersburg, MD USA
[17] Sarah Cannon Res Inst, Nashville, TN USA
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中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
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