The positive effect of spermidine in older adults suffering from dementia after 1 year

被引:4
|
作者
Pekar, Thomas [1 ]
Wendzel, Aribert [2 ]
Jarisch, Reinhart [3 ]
机构
[1] Univ Appl Sci Wiener Neustadt, Biomed Sci, Johannes Gutenberg Str 3, A-2700 Wiener Neustadt, Austria
[2] Gepflegt Wohnen Hart Bei Graz GmbH, Pachern Hauptstr 152d, A-8075 Hart Bei Graz, Austria
[3] FAZ Floridsdorfer Allergiezentrum, Pius Parsch Pl 1-3, A-1210 Vienna, Austria
关键词
Alzheimer; Nutrition; Biogen amines; Memory perfomance; CERAD-Plus;
D O I
10.1007/s00508-023-02226-z
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
BackgroundA positive effect of the effect of a 3-month oral spermidine intake on memory performance has already been demonstrated. The continuation of this study aimed to examine whether there could be observed an improvement in memory performance after one year.Method45 residents of the nursing home "Gepflegt Wohnen" in Hart bei Graz, Styria, Austria, were given a daily dose of 3.3 mg spermidine in their diet for one year.ResultsThe comparison of the MMSE test results at baseline and after one year demonstrated a significant (p < 0.001) difference. The mean improvement is 5 points.ConclusionThe new results confirm the already proven positive effect of oral spermidine intake on memory performance.
引用
收藏
页码:64 / 66
页数:3
相关论文
共 50 条
  • [41] Effect of Statin Therapy on Cognitive Decline and Incident Dementia in Older Adults
    Zhou, Zhen
    Ryan, Joanne
    Ernst, Michael E.
    Zoungas, Sophia
    Tonkin, Andrew M.
    Woods, Robyn L.
    McNeil, John J.
    Reid, Christopher
    Curtis, Andrea J.
    Wolfe, Rory
    Wrigglesworth, Jo
    Shah, Raj C.
    Storey, Elsdon
    Murray, Anne
    Orchard, Suzanne G.
    Nelson, Mark R.
    CIRCULATION, 2021, 144
  • [42] Effect of Statin Therapy on Cognitive Decline and Incident Dementia in Older Adults
    Zhou, Zhen
    Ryan, Joanne
    Ernst, Michael E.
    Zoungas, Sophia
    Tonkin, Andrew M.
    Woods, Robyn L.
    McNeil, John J.
    Reid, Christopher M.
    Curtis, Andrea J.
    Wolfe, Rory
    Wrigglesworth, Jo
    Shah, Raj C.
    Storey, Elsdon
    Murray, Anne
    Orchard, Suzanne G.
    Nelson, Mark R.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2021, 77 (25) : 3145 - 3156
  • [43] Complications affecting the functional outcome after 1 year in older adults with severe head injury
    Lin, Ming-Hsiu
    Lu, Chih-Cheng
    Chang, Chia-Hao
    Tsai, Tsung-Chih
    FORMOSAN JOURNAL OF SURGERY, 2023, 56 (01) : 16 - 21
  • [44] Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization
    Walter, LC
    Brand, RJ
    Counsell, SR
    Palmer, RM
    Landefeld, CS
    Fortinsky, RH
    Covinsky, KE
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2001, 285 (23): : 2987 - 2994
  • [45] Development and validation of a prognostic index for 1-year mortality in older adults after hospitalization
    Walter, L
    Covinsky, K
    Brand, R
    Counsell, S
    Landefeld, C
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2000, 48 (08) : S123 - S123
  • [46] Predictors of Mortality Up to 1 Year After Emergency Major Abdominal Surgery in Older Adults
    Cooper, Zara
    Mitchell, Susan L.
    Gorges, Rebecca J.
    Rosenthal, Ronnie A.
    Lipsitz, Stuart R.
    Kelley, Amy S.
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2015, 63 (12) : 2572 - 2579
  • [47] Use of Medications of Questionable Benefit During the Last Year of Life of Older Adults With Dementia
    Morin, Lucas
    Vetrano, Davide L.
    Grande, Giulia
    Fratiglioni, Laura
    Fastbom, Johan
    Johnell, Kristina
    JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION, 2017, 18 (06) : 551.e1 - 551.e7
  • [48] Predicting 2-Year Risk of Developing Pneumonia in Older Adults without Dementia
    Jackson, Michael L.
    Walker, Rod
    Lee, Sei
    Larson, Eric
    Dublin, Sascha
    JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2016, 64 (07) : 1439 - 1447
  • [49] Internet search for counseling offers for older adults suffering from visual impairment
    Himmelsbach, I.
    Lipinski, J.
    Putzke, M.
    OPHTHALMOLOGE, 2016, 113 (11): : 933 - 942
  • [50] Psychological well-being in older adults suffering from chronic headache
    Jelicic, M
    Kempen, GIJM
    Passchier, J
    HEADACHE, 1998, 38 (04): : 292 - 294