The relevance of oral food challenge in a patient allergic to peanut and tree nuts

被引:0
|
作者
Limao, Rita [1 ,3 ]
Bartolome, Borja [2 ]
Duarte, Fatima Cabral [1 ]
机构
[1] CHU Lisboa Norte, Immunoallergol Dept, Lisbon, Portugal
[2] Roxall Espana, Res & Dev Dept, Bilbao, Spain
[3] CHU Lisboa Norte, Hosp Santa Maria, Allergy & Immunol Dept, Portugal Ave Prof Egas Moniz, P-1649028 Lisbon, Portugal
关键词
Allergy; oral food challenge; peanut; skin prick test; tree nuts; PREVENTION; UPDATE;
D O I
10.5415/apallergy.0000000000000109
中图分类号
R392 [医学免疫学];
学科分类号
100102 ;
摘要
Peanut allergy is one of the most common food allergies in childhood. In vitro cross-sensitization between peanut and tree nuts (TN) is high, but only a subgroup of patients allergic to peanut will have a concomitant allergy to one or several TN. In this article, the authors report a case of a 12-year-old boy who experienced 1 episode of lips and mouth itching, generalized urticarial, and eyelid angioedema 20 minutes after ingestion of peanut at 4 years of age. The immunoallergological study revealed the presence of a concomitant allergy to peanut, pistachio, and cashew confirmed with medically supervised oral food challenges (OFC) in a child who had never eaten these TN. The mechanism of IgE-mediated hypersensitivity was demonstrated by positive skin prick tests (SPT) with commercial extracts, although the specific IgE (sIgE) for these foods was negative. As described in the literature, we concluded that serum peanut and TN sIgE measurements have lower sensitivity than SPT to assess IgE sensitization, and OFC is the gold standard for accurate diagnosis of food allergy. We highlight the relevance of excluding or confirming TN allergy in a peanut-allergic patient who had never ingested certain TN, and of knowing the clinical relevant cross-reactivity patterns between TN, pistachio/cashew, and walnut/pecan, that could reduce the need for OFC in clinical practice, reducing allergy rates and financial and health burdens of food allergy.
引用
收藏
页码:132 / 134
页数:3
相关论文
共 50 条
  • [21] Food allergy to tree nuts, peanut and sesame seeds: sensitization and clinical reactivity patterns
    Vasconcelos, M. J.
    Carolino, F.
    Silva, D.
    Coimbra, A.
    [J]. ALLERGY, 2018, 73 : 496 - 496
  • [22] Comparative Analysis of Symptom Profiles during oral Allergen Challenge in Children and Adults with Peanut and/or Tree Nuts Allergy - exploratory Cross-sectional Analysis of the FOOD@ Project
    Dobbertin-Welsch, J.
    Alexiou, A.
    Unterleider, N.
    Tissen-Diabate, T.
    Hoefer, V.
    Doelle-Bierke, S.
    Trendelenburg, V.
    Kalb, B.
    Meixner, L.
    Roll, S.
    Worm, M.
    Beyer, K.
    [J]. ALLERGOLOGIE, 2022, 45 (08) : 616 - 617
  • [23] Tree nuts and peanut allergy - characterisation of a population
    Luz, S.
    Lopes, A.
    Spinola, Santos A.
    Alves, R.
    Costa, C.
    Maria, Conceicao S.
    Barbosa, M.
    [J]. ALLERGY, 2008, 63 : 293 - 293
  • [24] Safe selection of children with a suspected food allergy to introduce peanut or tree nuts at home
    de Weger, W. W.
    Herpertz, C. E. M.
    van Der Meulen, G. N.
    Bangma, H.
    Kastelijn, W.
    van Lente, L.
    Koppelman, G. H.
    Sprikkelman, A. B.
    Kamps, A. W. A.
    [J]. CLINICAL AND EXPERIMENTAL ALLERGY, 2024, 54 (03): : 216 - 218
  • [25] Peanut and tree nut allergic reactions in restaurants and other food establishments
    Furlong, TJ
    DeSimone, J
    Sicherer, SH
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2001, 108 (05) : 867 - 870
  • [26] Markers associated with adverse reactions during peanut oral food challenge after peanut oral immunotherapy
    Kim, Erin
    Binstadt, Bryce
    Ott, Nancy
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2024, 153 (02) : AB121 - AB121
  • [27] The Role of Oral Food Challenge in Peanut-Sensitized Individuals
    Levy, Michael B.
    Nachshon, Liat
    Goldberg, Michael R.
    Yechiam-Caspi, Hadas
    Golobov, Keren
    Elizur, Arnon
    Katz, Yitzhak
    [J]. JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 137 (02) : AB134 - AB134
  • [28] Organ-specific symptom patterns during oral food challenge in children with peanut and tree nut allergy
    Dobbertin-Welsch, Josefine
    Staudacher, Olga
    Yuerek, Songuel
    Trendelenburg, Valerie
    Tschirner, Sebastian
    Ziegert, Mandy
    Ahrens, Frank
    Millner-Uhlemann, Martina
    Buesing, Susanne
    Striegel, Anne
    Ott, Hagen
    Arens, Alisa
    Gappa, Monica
    Lange, Lars
    Gernert, Sunhild
    Niggemann, Bodo
    Beyer, Kirsten
    [J]. PEDIATRIC ALLERGY AND IMMUNOLOGY, 2022, 33 (05)
  • [29] GOLDEN PEANUT AND TREE NUTS INVESTS TO EXPAND PEANUT OIL PRODUCTION
    不详
    [J]. AGRO FOOD INDUSTRY HI-TECH, 2015, 26 (04): : 63 - 63
  • [30] Phenotypical characterization of peanut allergic children with differences in cross-allergy to tree nuts and other legumes
    Cousin, Mathias
    Verdun, Stephane
    Seynave, Maxime
    Vilain, Anne-Christine
    Lansiaux, Amelie
    Decoster, Anne
    Sauvage, Christine
    [J]. PEDIATRIC ALLERGY AND IMMUNOLOGY, 2017, 28 (03) : 245 - 250