Inflammatory Indicators in Peripheral Blood in Sudden Sensorineural Hearing Loss Patients With Different Shape of Audiograms

被引：4
|
作者：
Yao, Yuting [1 ,2 ]
Guo, Qinghua [1 ,3 ]
Luo, Wei [2 ]
Yang, Ming [3 ]
Liu, Jing [1 ,4 ]
Hou, Jie [1 ,4 ]
She, Wandong [1 ,4 ]
机构：
[1] Nanjing Univ Chinese Med, Dept Otolaryngol Head & Neck Surg, Nanjing Drum Tower Hosp, Clin Coll Tradit Chinese & Western Med, Nanjing 210008, Peoples R China
[2] Nanjing Univ, Jinling Hosp, Qinhuai Med Ctr, Nanjing, Peoples R China
[3] Nanjing Univ Chinese Med, Nanjing Integrated Tradit Chinese & Western Med H, Nanjing, Peoples R China
[4] Nanjing Univ, Dept Otolaryngol Head & Neck Surg, Affiliated Hosp, Nanjing Drum Tower Hosp,Med Sch, Nanjing, Peoples R China
来源：
ENT-EAR NOSE & THROAT JOURNAL | 2023年 / 102卷 / 02期
关键词：
sudden sensorineural hearing loss; audiogram shapes; neutrophil-to-lymphocyte ratio; monocyte-to-lymphocyte ratio; systemic immune index; inflammation; TO-LYMPHOCYTE RATIO; NEUTROPHIL; PLATELET;
D O I：
10.1177/01455613221132115
中图分类号：
R76 [耳鼻咽喉科学];
学科分类号：
100213 ;
摘要：
Objective: A retrospective study was conducted to explore the immune-inflammatory responses in sudden sensorineural hearing Loss (SSNHL) patients with different audiogram shapes. Methods: One hundred and ten inpatients with SSNHL were assigned to 4 subgroups according to the audiogram shape and treated with systemic methylprednisolone. The numbers of white blood cells, neutrophils, lymphocytes, platelets, and monocytes were counted. The neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), and the monocyte-to-lymphocyte ratio (MLR) were calculated and statistically analyzed. Results: Neutrophil-to-lymphocyte ratio, MLR, and systemic immune index (SII) of SSNHL patients were significantly higher than the control group, while PLR was not statistically significant. There were no statistical differences in NLR, PLR, MLR, and SII among the 4 subgroups. Conclusion: Immune-inflammatory response may be a common pathogenesis in all SSNHL patients with different audiogram shapes. The predictive value of these hematologic markers needs further research in the future.
引用
收藏
页码：90 / 95
页数：6
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