Toll-like receptors and Streptococcus mutans: An updated review article

被引：0

作者：

Al-Alawi, Fatima Zuhair Muhammad ^{[1
]}

Kariminik, Ashraf ^{[2
]}

Tajbakhsh, Elaheh ^{[3
]}

机构：

[1] Islamic Azad Univ, Dept Microbiol, Sci & Res Branch, Tehran, Iran

[2] Islamic Azad Univ, Dept Microbiol, Kerman Branch, Kerman, Iran

[3] Islamic Azad Univ, Dept Microbiol, Shahrekord Branch, Shahrekord, Iran

来源：

ALLERGOLOGIA ET IMMUNOPATHOLOGIA | 2024年 / 52卷 / 01期

关键词：

Streptococcus mutans; Toll-like Receptors; Inflammation; CYTOKINE PRODUCTION; LIPOTEICHOIC ACID; CROSS-TALK; KAPPA-B; ACTIVATION; RESPONSES; RECOGNITION; STRAINS; PATHWAY; ANTIGEN;

D O I：

10.15586/aei.v52i1.935

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

It has been reported that toll-like receptors (TLRs) are the main innate immune receptors that recognize gram-positive pathogen-associated molecular patterns (PAMPs). The molecules can induce expression of the innate immune-related molecules that are essential against the bacteria. Streptococcus mutans (S. mutans) is a potential caries-associated pathogen, and innate immunity plays a key role in inhibiting its development and the progression of inflammatory responses. Recently, the roles played by TLRs against S. mutans and the induction of inflammatory responses were evaluated by several investigations. This review article discusses updated information regarding the roles played by TLRs and their potential therapeutic effects against S. mutans. (c) 2024 Codon Publications. Published by Codon Publications.

引用

页码：79 / 84

页数：6

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