A phase I study of bintrafusp alfa and NHS-IL12 (M9241) alone and in combination with stereotactic body radiation therapy (SBRT) in patients with metastatic genitourinary (GU) malignancies.

被引：0

作者：

Simon, Nicholas I.

Niglio, Scot Anthony

Chandran, Elias

Iannantuono, Giovanni Maria

Boudjadi, Salah

Banday, Rouf

Girardi, Daniel da Motta

Cordes, Lisa M.

Ley, Lisa

Gurram, Sandeep

Kydd, Andre Rashad

Jones, Jennifer C.

Salerno, Kilian Elizabeth

Patel, Krishnan

Valera, Vladimir

Parnes, Howard L.

Figg, William Douglas

Gulley, James L.

Schlom, Jeffrey

Apolo, Andrea B.

机构：

[1] NCI, Ctr Canc Res, NIH, Bethesda, MD 20892 USA

[2] NYU, Langone Laura & Isaac Perlmutter Canc Ctr, New York, NY USA

[3] NCI, Genitourinary Malignancies Branch, NIH, Bethesda, MD 20892 USA

[4] NCI, Genitourinary Malignancies Branch, CCR, NIH, Bethesda, MD 20892 USA

[5] NCI, Bethesda, MD 20892 USA

[6] Hosp Sirio Libanes, Brasilia, DF, Brazil

[7] NIH, Bldg 10, Bethesda, MD 20892 USA

[8] NCI, NIH, Bethesda, MD 20892 USA

[9] NCI, Radiat Oncol Branch, NIH, Bethesda, MD 20892 USA

[10] NCI, Urol Oncol Branch, Bethesda, MD 20892 USA

[11] NCI, Ctr Immunooncol, NIH, Bethesda, MD 20892 USA

[12] NCI, Ctr Immunooncol, Ctr Canc Res, NIH, Bethesda, MD 20892 USA

来源：

JOURNAL OF CLINICAL ONCOLOGY | 2023年 / 41卷 / 16期

基金：

美国国家卫生研究院;

关键词：

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

4571

引用

页数：1

共 9 条

[1] A phase I study of bintrafusp alfa (M7824) and NHS-IL12 (M9241) alone and in combination with stereotactic body radiation therapy (SBRT) in adults with metastatic non-prostate genitourinary malignancies.
Niglio, Scot Anthony
Girardi, Daniel da Motta
Cordes, Lisa M.
Ley, Lisa
Mallek, Marissa
Ortiz, Olena Sierra
Cadena, Jacqueline
Diaz, Carlos
Chalfin, Heather
Kydd, Andre
Costello, Rene
Marciscano, Ariel E.
Jones, Jennifer C.
Salerno, Kilian Elizabeth
Valera, Vladimir
Figg, William Douglas
Dahut, William L.
Gulley, James L.
Schlom, Jeffrey
Apolo, Andrea B.
JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
[2] PHASE I/II EVALUATION OF THE COMBINATION OF ENTINOSTAT, M9241 AND BINTRAFUSP ALFA IN PATIENTS WITH ADVANCED HPV RELATED MALIGNANCIES
Strauss, Julius
Floudas, Charalampos
Pastor, Danielle
Redman, Jason
Francis, Deneise
Lamping, Elizabeth
Cordes, Lisa
Marte, Jennifer
Donahue, Renee
Jochems, Caroline
Gameiro, Sofia
Schlom, Jeffrey
Gulley, James
JOURNAL FOR IMMUNOTHERAPY OF CANCER, 2022, 10 : A797 - A797
[3] Phase II evaluation of the triple combination of PDS0101, M9241, and bintrafusp alfa in patients with HPV 16 positive malignancies.
Strauss, Julius
Floudas, Charalampos S.
Sater, Houssein Abdul
Manu, Michell
Lamping, Elizabeth
Francis, Deneise C.
Cordes, Lisa M.
Marte, Jenn
Donahue, Renee Nicole
Jochems, Caroline
Redman, Jason
Madan, Ravi Amrit
Bilusic, Marijo
Karzai, Fatima
Norberg, Scott
Hinrichs, Christian S.
Wood, Lauren V.
Bedu-Addo, Frank K.
Schlom, Jeffrey
Gulley, James L.
JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
[4] A phase I/II study of bintrafusp alfa and NHS-IL12 in combination with docetaxel in adults with metastatic castration sensitive (mCSPC) and castration-resistant prostate cancer (mCRPC).
Atiq, Mohammad O.
Bilusic, Marijo
Karzai, Fatima
Cordes, Lisa M.
Strauss, Julius
Sater, Houssein Abdul
Redman, Jason
Floudas, Charalampos S.
Hodge, James W.
Gameiro, Sofia
Figg, William Douglas
Schlom, Jeffrey
Dahut, William L.
Gulley, James L.
Madan, Ravi Amrit
JOURNAL OF CLINICAL ONCOLOGY, 2021, 39 (15)
[5] Phase Ib, open-label, dose-escalation study of M9241 (NHS-IL12) plus avelumab in patients (pts) with advanced solid tumours
Strauss, J.
Vugmeyster, Y.
Sznol, M.
Pachynski, R. K.
Trang, K.
Chennoufi, S.
Gulley, J. L.
ANNALS OF ONCOLOGY, 2019, 30
[6] A phase I study of the combination of atezolizumab, tiragolumab, and stereotactic body radiation therapy in patients with metastatic multiorgan cancer
Roussot, Nicolas
Fumet, Jean-David
Limagne, Emeric
Thibaudin, Marion
Hervieu, Alice
Hennequin, Audrey
Zanetta, Sylvie
Dalens, Lorraine
Fourrier, Theo
Galland, Loick
Jacob, Pierre
Bertaut, Aurelie
Rederstorff, Emilie
Chevalier, Cedric
Ghirardi, Sarah
Gilbert, Elodie
Khoukaz, Azzat
Martin, Etienne
Nicolet, Constance
Quivrin, Magali
Thibouw, David
Vulquin, Noemie
Truc, Gilles
Rouffiac, Magali
Ghiringhelli, Francois
Mirjolet, Celine
BMC CANCER, 2023, 23 (01)
[7] A phase I study of the combination of atezolizumab, tiragolumab, and stereotactic body radiation therapy in patients with metastatic multiorgan cancer
Nicolas Roussot
Jean-David Fumet
Emeric Limagne
Marion Thibaudin
Alice Hervieu
Audrey Hennequin
Sylvie Zanetta
Lorraine Dalens
Théo Fourrier
Loick Galland
Pierre Jacob
Aurélie Bertaut
Emilie Rederstorff
Cédric Chevalier
Sarah Ghirardi
Elodie Gilbert
Azzat Khoukaz
Etienne Martin
Constance Nicolet
Magali Quivrin
David Thibouw
Noémie Vulquin
Gilles Truc
Magali Rouffiac
Francois Ghiringhelli
Céline Mirjolet
BMC Cancer, 23
[8] Phase I/II study of stereotactic body radiation therapy (SBRT) to metastatic lesions in the liver or lung in combination with monoclonal antibody to OX40 in patients with progressive metastatic breast cancer (mBC) after systemic therapy.
Crittenden, Marka
Conlin, Alison Katherine
Moxon, Nicole
Curti, Brendan D.
JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
[9] Final Results of a Phase I Prospective Trial Evaluating the Combination of Stereotactic Body Radiation Therapy (SBRT) with Concurrent Pembrolizumab in Patients with Metastatic Non-Small Cell Lung Cancer (NSCLC) or Melanoma
Campbell, A. M.
Herbst, R. S.
Gettinger, S. N.
Goldberg, S. B.
Kluger, H. M.
Chiang, A. C.
Lilenbaum, R. C.
Schalper, K. A.
Sowell, R.
Kaech, S.
Decker, R. H.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2018, 102 (03): : S18 - S19

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