A phase I study of the combination of atezolizumab, tiragolumab, and stereotactic body radiation therapy in patients with metastatic multiorgan cancer

被引：0
|
作者：
Nicolas Roussot
Jean-David Fumet
Emeric Limagne
Marion Thibaudin
Alice Hervieu
Audrey Hennequin
Sylvie Zanetta
Lorraine Dalens
Théo Fourrier
Loick Galland
Pierre Jacob
Aurélie Bertaut
Emilie Rederstorff
Cédric Chevalier
Sarah Ghirardi
Elodie Gilbert
Azzat Khoukaz
Etienne Martin
Constance Nicolet
Magali Quivrin
David Thibouw
Noémie Vulquin
Gilles Truc
Magali Rouffiac
Francois Ghiringhelli
Céline Mirjolet
机构：
[1] Center Georges François Leclerc,Department of Medical Oncology
[2] Center GF Leclerc,Department of Radiotherapy
[3] Cancer Biology Transfer Platform,Department of Epidemiology and Biostatistics
[4] GIMI Genetic and Immunology Medical Institute,Radiation Oncology Department, Preclinical Radiation Therapy and Radiobiology Unit
[5] University of Burgundy-Franche Comté,undefined
[6] UMR INSERM 1231,undefined
[7] Center GF Leclerc,undefined
[8] Center GF Leclerc,undefined
来源：
BMC Cancer | / 23卷
关键词：
Non-small cell lung cancer; Renal cell cancer; Bladder cancer; Head and neck cancer; PDL-1; TIGIT; Atezolizumab; Tiragolumab; Stereotactic body radiation therapy; SBRT; Immunotherapy;
D O I：
暂无
中图分类号：
学科分类号：
摘要：
引用
收藏
相关论文
共 50 条
  • [1] A phase I study of the combination of atezolizumab, tiragolumab, and stereotactic body radiation therapy in patients with metastatic multiorgan cancer
    Roussot, Nicolas
    Fumet, Jean-David
    Limagne, Emeric
    Thibaudin, Marion
    Hervieu, Alice
    Hennequin, Audrey
    Zanetta, Sylvie
    Dalens, Lorraine
    Fourrier, Theo
    Galland, Loick
    Jacob, Pierre
    Bertaut, Aurelie
    Rederstorff, Emilie
    Chevalier, Cedric
    Ghirardi, Sarah
    Gilbert, Elodie
    Khoukaz, Azzat
    Martin, Etienne
    Nicolet, Constance
    Quivrin, Magali
    Thibouw, David
    Vulquin, Noemie
    Truc, Gilles
    Rouffiac, Magali
    Ghiringhelli, Francois
    Mirjolet, Celine
    BMC CANCER, 2023, 23 (01)
  • [2] Phase Ib study of the anti-TIGIT antibody tiragolumab in combination with atezolizumab in patients with metastatic esophageal cancer
    Wainberg, Z.
    Matos, I.
    Delord, J.
    Cassier, P.
    Gil-Martin, M.
    Kim, T.
    LoRusso, P.
    Bahleda, R.
    Italiano, A.
    Mendus, D.
    Hoang, T.
    Xue, C.
    Wen, X.
    Carvalho, O.
    Pham, T.
    Patil, N.
    Meng, R.
    Bendell, J.
    Cervantes, A.
    Cho, B.
    ANNALS OF ONCOLOGY, 2021, 32 : S227 - S228
  • [3] Phase I study of the anti-TIGIT antibody tiragolumab in combination with atezolizumab in Japanese patients with advanced or metastatic solid tumors
    Yamamoto, Noboru
    Koyama, Takafumi
    Sato, Jun
    Yoshida, Tatsuya
    Sudo, Kazuki
    Iwasa, Satoru
    Kondo, Shunsuke
    Yonemori, Kan
    Kawasaki, Atsuko
    Satake, Kyoko
    Shibata, Shoyo
    Shimizu, Toshio
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2024, 94 (01) : 109 - 115
  • [4] A Phase I Trial of Atezolizumab and Varlilumab in Combination With Radiation in Patients With Metastatic NSCLC
    Malhotra, Jyoti
    Lin, Yong
    Patel, Malini
    Yellin, Michael J.
    Zachariah, Emmanuel
    Krier, Curtis
    Saxena, Ankit
    Jabbour, Salma K.
    JTO CLINICAL AND RESEARCH REPORTS, 2024, 5 (08):
  • [5] Trial in progress: Phase II study of stereotactic body radiation therapy and atezolizumab in the management of recurrent, persistent, or metastatic cervical cancer.
    Ahmed, Kamran A.
    Kim, Youngchul
    Apte, Sachin M.
    Chon, Hye Sook
    Chern, Jing-Yi
    Conejo-Garcia, Jose
    Fernandez, Daniel Celestino
    Hoffman, Mitchel
    Kim, Sungjune
    Lam, Cesar
    Montejo, Michael E.
    Shahzad, Mian M.
    Wenham, Robert Michael
    JOURNAL OF CLINICAL ONCOLOGY, 2019, 37 (15)
  • [6] Phase I pharmacokinetic, safety, and preliminary efficacy study of tiragolumab in combination with atezolizumab in Chinese patients with advanced solid tumors
    Shemesh, Colby S.
    Wang, Yongsheng
    An, Andrew
    Ding, Hao
    Chan, Phyllis
    Liu, Qi
    Chen, Yih-Wen
    Wu, Benjamin
    Wu, Qiong
    Wang, Xian
    CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2024, 94 (01) : 45 - 55
  • [7] A Phase I Trial of Atezolizumab and Varlilumab in Combination With Radiation in Patients with Metastatic Non-Small Cell Lung Cancer
    Malhotra, J.
    Lin, Y.
    Gonzales, A.
    Patel, M.
    Chan, N.
    Aisner, J.
    Jabbour, S.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S948 - S948
  • [8] Phase I/II Study of Stereotactic Body Radiation Therapy for Pulmonary Metastases in Pediatric Patients
    Liu, Kevin X.
    Chen, Yu-Hui
    Kozono, David
    Mak, Raymond H.
    Boyle, Patrick J.
    Janeway, Katherine A.
    Mullen, Elizabeth A.
    Marcus, Karen J.
    ADVANCES IN RADIATION ONCOLOGY, 2020, 5 (06) : 1267 - 1273
  • [9] Phase I Trial of Stereotactic Body Radiation Therapy (SBRT) to Multiple Metastatic Sites: A NRG Oncology Study
    Chmura, S. J.
    Winter, K.
    Salama, J. K.
    Robinson, C. G.
    Pisansky, T. M.
    Borges, V.
    Al-Hallaq, H. A.
    Matuszak, M. M.
    Park, S. S.
    Gonzalez, V. J.
    Hasan, Y.
    Bazan, J. G.
    Wong, P.
    Yoon, H. A.
    Horton, J. K.
    Gan, G. N.
    Milano, M. T.
    Sigurdson, E. R.
    Moughan, J.
    White, J. R.
    INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 2018, 102 (03): : S68 - S69
  • [10] Phase I/II study of stereotactic body radiation therapy (SBRT) to metastatic lesions in the liver or lung in combination with monoclonal antibody to OX40 in patients with progressive metastatic breast cancer (mBC) after systemic therapy.
    Crittenden, Marka
    Conlin, Alison Katherine
    Moxon, Nicole
    Curti, Brendan D.
    JOURNAL OF CLINICAL ONCOLOGY, 2015, 33 (15)
12345