RIFM fragrance ingredient safety assessment, o-methoxybenzaldehyde, CAS Registry Number 135-02-4

被引：0

作者：

Api, A. M. ^{[1
]}

Belsito, D. ^{[2
]}

Botelho, D. ^{[1
]}

Bruze, M. ^{[3
]}

Burton Jr, G. A. ^{[4
]}

Cancellieri, M. A. ^{[1
]}

Chon, H. ^{[1
]}

Dagli, M. L. ^{[5
]}

Dekant, W. ^{[6
]}

Deodhar, C. ^{[1
]}

Fryer, A. D. ^{[7
]}

Jones, L. ^{[1
]}

Joshi, K. ^{[1
]}

Kumar, M. ^{[1
]}

Lapczynski, A. ^{[1
]}

Lavelle, M. ^{[1
]}

Lee, I. ^{[1
]}

Liebler, D. C. ^{[1
,8
]}

Moustakas, H. ^{[1
]}

Muldoon, J. ^{[1
]}

Penning, T. M. ^{[9
]}

Ritacco, G. ^{[1
]}

Romine, J. ^{[1
]}

Sadekar, N. ^{[1
]}

Schultz, T. W. ^{[10
]}

Selechnik, D. ^{[1
]}

Siddiqi, F. ^{[1
]}

Sipes, I. G. ^{[11
]}

Sullivan, G. ^{[1
]}

Thakkar, Y. ^{[1
]}

Tokura, Y. ^{[12
]}

机构：

[1] Res Inst Fragrance Mat Inc, 50 Tice Blvd, Woodcliff Lake, NJ 07677 USA

[2] Columbia Univ, Med Ctr, Dept Dermatol, Expert Panel Fragrance Safety, 161 Ft Washington Ave, New York, NY 10032 USA

[3] Malmo Univ Hosp, Dept Occupat & Environm Dermatol, Expert Panel Fragrance Safety, Sodra Forstadsgatan 101,Entrance 47, SE-20502 Malmo, Sweden

[4] Univ Michigan, Sch Nat Resources & Environm, Expert Panel Fragrance Safety, Dana Bldg G110,440 Church St, Ann Arbor, MI 58109 USA

[5] Univ Sao Paulo, Sch Vet Med & Anim Sci, Dept Pathol, Expert Panel Fragrance Safety, Ave Prof Dr Orlando Marques de Paiva 87, BR-05508900 Sao Paulo, Brazil

[6] Univ Wurzburg, Dept Toxicol, Versbacher Str 9, D-97078 Wurzburg, Germany

[7] Oregon Hlth & Sci Univ, Dept Pathol, 3181 SW Sam Jackson Pk Rd, Portland, OR 97239 USA

[8] Vanderbilt Univ, Sch Med, Ctr Mol Toxicol, Dept Biochem, 638 Robinson Res Bldg 2200 Pierce Ave, Nashville, TN 37232 USA

[9] Univ Penn, Ctr Excellence Environm Toxicol, Perelman Sch Med, Expert Panel Fragrance Safety, 1316 Biomed Res Bldg BRB 2-3,421 Curie Blvd, Philadelphia, PA 19104 USA

[10] Univ Tennessee, Coll Vet Med, Dept Comparat Med, 2407 River Dr, Knoxville, TN 37901 USA

[11] Univ Arizona, Coll Med, Dept Pharmacol, Expert Panel Fragrance Safety, 1501 North Campbell Ave,POB 245050, Tucson, AZ 85724 USA

[12] Hamamatsu Univ Sch Med, Expert Panel Fragrance Safety, Journal Dermatol Sci JDS, Higashi Ku, 1-20-1 Handayama, Hamamatsu, Shizuoka 4313192, Japan

来源：

FOOD AND CHEMICAL TOXICOLOGY | 2024年 / 183卷

关键词：

PERSONAL CARE; CONSUMER EXPOSURE; MODEL; GENOTOXICITY; ABSORPTION; COSMETICS; THRESHOLD;

D O I：

10.1016/j.fct.2023.114417

中图分类号：

TS2 [食品工业];

学科分类号：

0832 ;

摘要：

There are insufficient toxicity data on o-methoxybenzaldehyde (CAS # 135-02-4). Hence, in silico evaluation was conducted to determine readacross analogs for this material. Based on structural similarity, reactivity, physical-chemical properties, and expert judgment, p-methox- ybenzaldehyde (CAS # 123-11-5) was identified as a read -across analog with sufficient data for toxicological evaluation.

引用

页数：11

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