A RAB transition orchestrates membrane trafficking in unconventional protein secretion

被引：0
|
作者：
Sun, Yuxin [1 ]
Zhang, Min [2 ]
Ge, Liang [1 ]
机构：
[1] Tsinghua Univ, Peking Univ Joint Ctr Life Sci, Beijing Frontier Res Ctr Biol Struct, Sch Life Sci,State Key Lab Membrane Biol, Beijing, Peoples R China
[2] Tsinghua Univ, Sch Pharmaceut Sci, State Key Lab Membrane Biol, Beijing, Peoples R China
来源：
JOURNAL OF CELL BIOLOGY | 2024年 / 223卷 / 02期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1083/jcb.202312096
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Sun et al. discusses recent work from Li et al. describing a cascade of RAB regulation in unconventional trafficking of PGP-1 to the cell surface in C. elegans. Rab GTPases function as intracellular molecular switches that regulate vesicular transport. In the current issue, Li et al. (https://doi.org/10.1083/jcb.202306107) revealed RAB-8 to RAB-11 transition governing the unconventional secretion of membrane proteins in the intestinal epithelium of C. elegans.
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页数：2
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