A RAB transition orchestrates membrane trafficking in unconventional protein secretion

被引：0
|
作者：
Sun, Yuxin [1 ]
Zhang, Min [2 ]
Ge, Liang [1 ]
机构：
[1] Tsinghua Univ, Peking Univ Joint Ctr Life Sci, Beijing Frontier Res Ctr Biol Struct, Sch Life Sci,State Key Lab Membrane Biol, Beijing, Peoples R China
[2] Tsinghua Univ, Sch Pharmaceut Sci, State Key Lab Membrane Biol, Beijing, Peoples R China
来源：
JOURNAL OF CELL BIOLOGY | 2024年 / 223卷 / 02期
基金：
中国国家自然科学基金;
关键词：
D O I：
10.1083/jcb.202312096
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Sun et al. discusses recent work from Li et al. describing a cascade of RAB regulation in unconventional trafficking of PGP-1 to the cell surface in C. elegans. Rab GTPases function as intracellular molecular switches that regulate vesicular transport. In the current issue, Li et al. (https://doi.org/10.1083/jcb.202306107) revealed RAB-8 to RAB-11 transition governing the unconventional secretion of membrane proteins in the intestinal epithelium of C. elegans.
引用
收藏
页数：2
相关论文
共 50 条
  • [1] Unconventional protein secretion - new perspectives in protein trafficking
    Denus, Morgane
    Fargues, William
    Filaquier, Aurore
    Neel, Eloise
    Marin, Philippe
    Parmentier, Marie-Laure
    Villeneuve, Julien
    M S-MEDECINE SCIENCES, 2024, 40 (03): : 267 - 274
  • [2] Coordination of RAB-8 and RAB-11 during unconventional protein secretion
    Li, Xinxin
    Liu, Bowen
    Wen, Yue
    Wang, Jiabin
    Guo, Yusong R.
    Shi, Anbing
    Lin, Long
    JOURNAL OF CELL BIOLOGY, 2023, 223 (02):
  • [3] Protein and membrane trafficking routes in plants: conventional or unconventional?
    Goring, Daphne R.
    Di Sansebastiano, Gian Pietro
    JOURNAL OF EXPERIMENTAL BOTANY, 2018, 69 (01) : 1 - 5
  • [4] The rab11 effector rab couplin protein (RCP) regulates adiponectin trafficking and secretion in adipocytes
    Carson, B. P.
    Del-Bas, J. Maria
    Mora, S.
    DIABETOLOGIA, 2011, 54 : S304 - S304
  • [5] Structural Basis of Membrane Trafficking by Rab Family Small G Protein
    Park, Hyun Ho
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2013, 14 (05): : 8912 - 8923
  • [6] Rab GTPases, Membrane Trafficking and Diseases
    Li, Guangpu
    CURRENT DRUG TARGETS, 2011, 12 (08) : 1188 - 1193
  • [7] Rab GTPases and Membrane Trafficking in Neurodegeneration
    Kiral, Ferdi Ridvan
    Kohrs, Friederike Elisabeth
    Jin, Eugene Jennifer
    Hiesinger, Peter Robin
    CURRENT BIOLOGY, 2018, 28 (08) : R471 - R486
  • [8] Unconventional protein trafficking in neurons
    Kennedy, M.
    JOURNAL OF NEUROCHEMISTRY, 2019, 150 : 42 - 42
  • [9] Unconventional protein secretion
    Ding, Yu
    Wang, Juan
    Wang, Junqi
    Stierhof, York-Dieter
    Robinson, David G.
    Jiang, Liwen
    TRENDS IN PLANT SCIENCE, 2012, 17 (10) : 606 - 615
  • [10] Identification and characterization of unconventional membrane protein trafficking regulators in Arabidopsis: A genetic approach
    Zhu, Ying
    Ji, Changyang
    Cao, Wenhan
    Shen, Jinbo
    Zhao, Qiong
    Jiang, Liwen
    JOURNAL OF PLANT PHYSIOLOGY, 2020, 252
12345