Dynamical analysis of a nonlinear fractional cervical cancer epidemic model with the nonstandard finite difference method

被引:6
|
作者
Butt, Asma Rashid [1 ]
Saqib, Aitzaz Ahmad [1 ]
Alshomrani, Ali Saleh [2 ]
Bakar, Abu [3 ]
Inc, Mustafa [4 ,5 ]
机构
[1] Univ Engn & Technol, Dept Math, Lahore, Pakistan
[2] King Abdulaziz Univ, Dept Math, Math Modelling & Appl Computat Res Grp MMAC, POB 80203, Jeddah 21589, Saudi Arabia
[3] Univ Punjab, Dept Math, Quaid E Eazam Campus, Lahore, Pakistan
[4] Firat Univ, Dept Math, Elazig TR-23119, Turkiye
[5] China Med Univ, Dept Med Res, Taichung 40402, Taiwan
关键词
Cervical cancer; Mathematical model; Caputo fractional operator; Sensitivity analysis; Nonstandard finite difference method; HUMAN-PAPILLOMAVIRUS; WOMEN; RISK;
D O I
10.1016/j.asej.2023.102479
中图分类号
T [工业技术];
学科分类号
08 ;
摘要
In this paper, we analyze the fractional compartmental model in the sense of Caputo derivative for the dynamics of the novel human papillomavirus, which causes cervical cancer. We study and investigate the dynamical analysis of a nonlinear fractional-order cervical cancer epidemic model with the nonstandard finite difference method. The newly proposed nonlinear fractional model is an extension of an integer-order cervical cancer mathematical model. We demonstrate the solution's existence, uniqueness, non-negativity, and boundedness by utilizing fundamental concepts of the fixed-point theory. The basic reproduction number, which analyzes whether or not the infection spreads to the population, is computed using the next-generation matrix method. We investigate the local and global asymptotic stability of the derived cervical-free and cervical-present equilibrium points and discuss the sensitivity of the basic reproduction number, which depends on the parameters of the proposed model. Furthermore, a mathematical simulation of the suggested continuous model is performed to evaluate the reported theoretical results using the nonstandard finite difference method. The acquired results are displayed, which show that a fractional parameter plays a pivotal role in controlling the cervical cancer.
引用
收藏
页数:12
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