GL0034 (Utreglutide), a novel, long acting, glucagon-like peptide 1 receptor agonist (GLP-1 RA), results of a phase 1 study in healthy individuals

被引：0
|
作者：
Thennati, Rajamannar [1 ]
Burade, Vinod [1 ]
Natarajan, Muthukumaran [1 ]
Shahi, Pradeep [1 ]
Nagaraja, Ravishankara [1 ]
Panchal, Satish [1 ]
Agrawal, Sudeep [1 ]
Jandrain, Bernard [2 ]
Duvauchelle, Thierry [3 ]
Pratley, Richard E. [4 ]
Thorens, Bernard [5 ]
Vilsboll, Tina [6 ]
机构：
[1] Sun Pharmaceut Ind Ltd, High Impact Innovat Sustainable Hlth Solut HISHS, Vadodara, India
[2] Acad Hosp Liege, ATC Co, Clin Pharmacol Unit, Nutr & Metab Disorders, Liege, Belgium
[3] Phaster1, Paris, France
[4] AdventHlth Translat Res Inst, Orlando, FL USA
[5] Univ Lausanne, Ctr Integrat Genom, Lausanne, Switzerland
[6] Univ Copenhagen, Steno Diabet Ctr, Clin Res, Copenhagen, Denmark
来源：
JOURNAL OF HEPATOLOGY | 2023年 / 78卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
THU-419
引用
收藏
页码：S607 / S608
页数：2
相关论文
共 50 条
  • [41] Description and application of a novel glucagon-like peptide-1 (GLP-1) radioimmunoassay
    B. Lelesz
    G. K. Tóth
    B. Peitl
    C. Hegedűs
    L. Drimba
    R. Sári
    Z. Szilvássy
    J. Németh
    Journal of Radioanalytical and Nuclear Chemistry, 2014, 299 : 157 - 164
  • [42] Peripheral Glucagon-like Peptide-1 (GLP-1) and Satiation
    Punjabi, Mukesh
    Arnold, Myrtha
    Geary, Nori
    Langhans, Wolfgang
    Pacheco-Lopez, Gustavo
    PHYSIOLOGY & BEHAVIOR, 2011, 105 (01) : 71 - 76
  • [43] Binding Kinetics, GLP-1 Receptor Internalization, and Effects on Insulin Secretion for GL0034 and Related GLP-1R Agonists
    Carrat, Gaelle
    Nguyen-Tu, Marie-Sophie
    Leclerc, Isabelle
    Thennati, Rajamannar
    Jones, Ben
    Tomas, Alejandra
    Rutter, Guy A.
    DIABETES, 2020, 69
  • [44] The role of glucagon-like peptide 1 (GLP-1) in addictive disorders
    Kruse Klausen, Mette
    Thomsen, Morgane
    Wortwein, Gitta
    Fink-Jensen, Anders
    BRITISH JOURNAL OF PHARMACOLOGY, 2022, 179 (04) : 625 - 641
  • [45] Glucagon-like peptide 1 (GLP-1) analogues and weight loss
    不详
    ARCHIVES OF DISEASE IN CHILDHOOD, 2020, 105 (07) : 663 - 663
  • [46] Aspiration risk with glucagon-like peptide 1 (GLP-1) agonists
    Marroquin-Harris, M.
    Olesnicky, B.
    ANAESTHESIA, 2023, 78 (12) : 1524 - 1524
  • [47] THE COLON AS A SOURCE FOR GLUCAGON-LIKE PEPTIDE-1 (GLP-1)
    HOLST, JJ
    OLESEN, KM
    GUDMANDHOYER, E
    DEACON, CF
    HANSEN, CP
    JOHNSEN, AH
    MIHOLIC, J
    NAUCK, M
    QUALMANN, C
    DIABETOLOGIA, 1995, 38 : A170 - A170
  • [48] Discovery of a Potent, Orally Efficacious Small Molecule Agonist of Glucagon-Like Peptide-1 (GLP-1) Receptor
    Bearss, David J.
    Lin, Chenyu
    Medley, Kyle
    Vankayalapati, Hariprasad
    DIABETES, 2024, 73
  • [49] A mechanism for agonist activation of the glucagon-like peptide-1 (GLP-1) receptor through modelling & molecular dynamics
    Santiago, Carla Gomez
    Paci, Emanuele
    Donnelly, Dan
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2018, 498 (02) : 359 - 365
  • [50] Efficacy and Safety of Glucagon-Like Peptide 1 (GLP-1) Receptor Agonist in Children With Chemotherapy-Induced Hyperglycemia
    Adly, Amira
    Ismail, Eman
    AlDagen, Manar
    Salah, Nouran
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2023, 23 : S238 - S238
12345