Development of light-induced disruptive liposomes (LiDL) as a photoswitchable carrier for intracellular substance delivery

被引：2
|
作者：
Tsuneishi, Taichi [1 ]
Kojima, Keiichi [1 ,2 ]
Kubota, Fumika [3 ]
Harashima, Hideyoshi [3 ]
Yamada, Yuma [3 ]
Sudo, Yuki [1 ,2 ]
机构：
[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Okayama 7008530, Japan
[2] Okayama Univ, Fac Med Dent & Pharmaceut Sci, Okayama 7008530, Japan
[3] Hokkaido Univ, Fac Pharmaceut Sci, Sapporo 0600812, Japan
来源：
CHEMICAL COMMUNICATIONS | 2023年 / 59卷 / 49期
关键词：
MECHANISM; PROTEIN;
D O I：
10.1039/d3cc02056h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Light-driven inward proton pump rhodopsin RmXeR was embedded in pH-sensitive liposomes. Substance release from the proteoliposomes was observed following light illumination both in vitro and in cells, indicating the successful production of light-induced disruptive liposomes (LiDL). Thus, LiDL is a photoswitchable carrier utilized for intracellular substance delivery.
引用
收藏
页码：7591 / 7594
页数：4
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