The field of Instrumentation and Measurement (IM) plays a crucial role in the advancement of healthcare technologies. In this paper, we provide an introduction and overview of methodologies, technologies, and applications in the realm of IM, with a focus on telemedicine, e-health, wearable devices, and the integration of Artificial Intelligence (AI). We address open problems and challenging topics within the IM framework and provide references to articles published in IM venues to support our discussion. Furthermore, we adhere to IEEE publication policies and publishing ethics throughout the paper.