共 50 条
Large-cell Neuroendocrine Carcinoma of the Lung with Carcinoid Syndrome
被引:1
|作者:
Yamamoto, Makoto
[1
]
Ito, Renma
[1
]
Tsujibata, Akihiko
[2
]
Morita, Hiroko
[1
]
Yoneda, Taro
[1
]
Matano, Yutaka
[1
]
Higashikata, Toshinori
[1
]
机构:
[1] Komatsu Municipal Hosp, Dept Internal Med, Komatsu, Japan
[2] Komatsu Municipal Hosp, Dept Pathol, Komatsu, Japan
关键词:
carcinoid syndrome;
large cell neuroendocrine carcinoma of the lung;
refractory diarrhea;
EPIDEMIOLOGY;
NEOPLASMS;
TUMORS;
D O I:
10.2169/internalmedicine.0099-22
中图分类号:
R5 [内科学];
学科分类号:
1002 ;
100201 ;
摘要:
A 76-year-old woman was admitted to our hospital for refractory diarrhea with a poor antidiarrheal effect. Chest and abdominal computed tomography revealed a 24x22-mm mass in the left upper lobe of lung and multiple masses in the liver. Urine 5-Hydroxy indol acetic acid was markedly elevated. A liver biopsy revealed large-cell neuroendocrine carcinoma with serotonin production, suggestive of a lung origin, and a lung biopsy revealed combined large-cell neuroendocrine carcinoma and squamous cell carcinoma. Therefore, we made a definitive diagnosis of carcinoid syndrome caused by large-cell neuroendocrine carcinoma of the lung. Although chemotherapy was performed after diagnosis, the patient died 50 days postadmission.
引用
收藏
页码:1557 / 1563
页数:7
相关论文