Organoids as a biomarker for personalized treatment in metastatic colorectal cancer: Drug screen optimization and correlation with patient response

被引：0
|
作者：
Smabers, L. P. [1 ]
Wensink, E. [1 ]
Verissimo, C. S. [2 ]
Koedoot, E. [2 ]
Doorn, M. [2 ]
Pitsa, K-C. [2 ]
Huismans, M. [3 ]
Baron, C. Higuera
Valkenburg-van Iersel, L. [4 ]
Brousali, A. [5 ]
Overmeer, R. [2 ]
Braat, M. [6 ]
Elias, S. [7 ]
Vries, R. [2 ]
Kranenburg, O. [8 ]
Koopman, M. [1 ]
Boj, S. [2 ]
Roodhart, J. M. L. [1 ]
机构：
[1] Univ Med Ctr Utrecht, Med Oncol Dept, Utrecht, Netherlands
[2] HUB Organoids, Oncol, Utrecht, Netherlands
[3] Univ Med Ctr Utrecht, Ctr Mol Med, Utrecht, Netherlands
[4] Maastricht Univ, Med Oncol Dept, Med Ctr, Maastricht, Netherlands
[5] Univ Med Ctr Utrecht, Utrecht Platform Organoid Technol UPORT, Utrecht, Netherlands
[6] Univ Med Ctr Utrecht, Radiol Dept, Utrecht, Netherlands
[7] Univ Med Ctr Utrecht, Julius Ctr Hlth Sci & Primary Care, Utrecht, Netherlands
[8] Univ Med Ctr Utrecht, Surg Oncol Dept, Utrecht, Netherlands
来源：
ANNALS OF ONCOLOGY | 2023年 / 34卷
关键词：
D O I：
10.1016/j.annonc.2023.09.1286
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
2258P
引用
收藏
页码：S1161 / S1162
页数：2
相关论文
共 50 条
  • [31] Drug screening by uniform patient derived colorectal cancer hydro-organoids
    Jung, Yong Hun
    Choi, Dong-Hee
    Park, Kyungwon
    Lee, Sat-Byol
    Kim, Jonghun
    Kim, Hyunho
    Jeong, Hyun-Woo
    Yang, Ji Hun
    Kim, Jin-A
    Chung, Seok
    Min, Byung Soh
    BIOMATERIALS, 2021, 276
  • [32] Personalized ctDNA Assay for MRD Detection and Treatment Response Monitoring in a Patient With Metastatic Lung Cancer
    Azzi, G.
    Goodman, M.
    Olshan, P.
    Billings, P.
    Aleshin, A.
    JOURNAL OF THORACIC ONCOLOGY, 2021, 16 (10) : S1024 - S1024
  • [33] Bevacizumab treatment in the elderly patient with metastatic colorectal cancer
    Di Bartolomeo, Maria
    Maggi, Claudia
    Ricchini, Francesca
    Pietrantonio, Filippo
    Iacovelli, Roberto
    de Braud, Filippo
    Inno, Alessandro
    CLINICAL INTERVENTIONS IN AGING, 2015, 10 : 127 - 133
  • [34] Cetuximab treatment in a patient with metastatic colorectal cancer and psoriasis
    Neyns, B.
    Meert, V.
    Vandenbroucke, E.
    CURRENT ONCOLOGY, 2008, 15 (04) : 196 - 197
  • [35] Patient-derived organoids model treatment response of metastatic gastrointestinal cancers
    Vlachogiannis, Georgios
    Hedayat, Somaieh
    Vatsiou, Alexandra
    Jamin, Yann
    Fernandez-Mateos, Javier
    Khan, Khurum
    Lampis, Andrea
    Eason, Katherine
    Huntingford, Ian
    Burke, Rosemary
    Rata, Mihaela
    Koh, Dow-Mu
    Tunariu, Nina
    Collins, David
    Hulkki-Wilson, Sanna
    Ragulan, Chanthirika
    Spiteri, Inmaculada
    Moorcraft, Sing Yu
    Chau, Ian
    Rao, Sheela
    Watkins, David
    Fotiadis, Nicos
    Bali, Maria
    Darvish-Damavandi, Mahnaz
    Lote, Hazel
    Eltahir, Zakaria
    Smyth, Elizabeth C.
    Begum, Ruwaida
    Clarke, Paul A.
    Eltahir, Zakaria
    Smyth, Elizabeth C.
    Begum, Ruwaida
    Clarke, Paul A.
    Hahne, Jens C.
    Dowsett, Mitchell
    de Bono, Johann
    Workman, Paul
    Sadanandam, Anguraj
    Fassan, Matteo
    Sansom, Owen J.
    Eccles, Suzanne
    Starling, Naureen
    Braconi, Chiara
    Sottoriva, Andrea
    Robinson, Simon P.
    Cunningham, David
    Valeri, Nicola
    SCIENCE, 2018, 359 (6378) : 920 - +
  • [36] Patient-Derived Organoids Predict Cancer Treatment Response
    不详
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2018, 319 (14): : 1427 - 1427
  • [37] Patient-Derived Cancer Organoids as Predictors of Treatment Response
    Verduin, Maikel
    Hoeben, Ann
    De Ruysscher, Dirk
    Vooijs, Marc
    FRONTIERS IN ONCOLOGY, 2021, 11
  • [38] Specific metabolic response of patient-derived organoids to curcumin of colorectal cancer
    Chen, Lin
    Dai, Zhihui
    Ge, Chengyang
    Huang, Dong
    Zhou, Xi
    Pan, Kailing
    Xu, Wenxia
    Fu, Jianfei
    Du, Jin lin
    JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 2022, 1203
  • [39] The role of biomarker in later-line treatment for metastatic colorectal cancer
    Kawakami, Takeshi
    Yamazaki, Kentaro
    JOURNAL OF GASTROINTESTINAL ONCOLOGY, 2023, 14 (02) : 1178 - 1180
  • [40] Correlation between rash and a positive drug response associated with bevacizumab in a patient with advanced colorectal cancer
    Saif, M. Wasif
    Longo, Walter L.
    Israel, Gary
    CLINICAL COLORECTAL CANCER, 2008, 7 (02) : 144 - 148
12345