Pathophysiology of chronic thromboembolic pulmonary hypertension and treatment of non-surgical (inoperable) forms

被引：0
|
作者：
Simonneau, G. [1 ,2 ,3 ]
Jais, X. [1 ,2 ,4 ]
Brenot, P. [1 ,3 ,4 ]
Alonso, C. G. [1 ,3 ,4 ]
Jevnikar, M. [1 ,2 ,4 ]
Fadel, E. [1 ,3 ,4 ]
Mercier, O. [1 ,3 ,4 ]
Montani, D. [1 ,2 ,4 ]
Humbert, M. [1 ,2 ,4 ]
机构：
[1] Univ Paris Saclay, Fac Med, F-94270 Le Kremlin Bicetre, France
[2] Hop Bicetre, Ctr Reference Hypertens Plum, F-94270 Le Kremlin Bicetre, France
[3] Hop Marie Lannelongue, Grp Hosp Paris St Joseph, F-92350 Le Plessis Robinson, France
[4] Inserm UMR S 999, F-94270 Le Kremlin Bicetre, France
来源：
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE | 2023年 / 207卷 / 01期
关键词：
Hypertension; Pulmonary; Thromboembolism; Endarterectomy; Angioplasty; Balloon; RISK-FACTORS; ANGIOPLASTY; RIOCIGUAT;
D O I：
10.1016/j.banm.2022.10.010
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of a frequent disease. The occlusion of pulmonary arteries by organized fibrotic material in com-bination with a secondary microvasculopathy of vessels < 500 & mu;, like that observed in idiopathic PAH, leads to increased pulmonary vascular resistance and progressive right heart failure. Today the prognostic of this disease has markedly improved with the availability, in addition to lifelong anticoagulation, of different treatment modalities including surgery, angioplasty and medical therapy with PAH drugs according to the localization and characteristics of observed lesions. & COPY; 2022 l'Academie nationale de medecine. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：32 / 37
页数：6
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