Pathophysiology of chronic thromboembolic pulmonary hypertension and treatment of non-surgical (inoperable) forms

被引：0
|
作者：
Simonneau, G. [1 ,2 ,3 ]
Jais, X. [1 ,2 ,4 ]
Brenot, P. [1 ,3 ,4 ]
Alonso, C. G. [1 ,3 ,4 ]
Jevnikar, M. [1 ,2 ,4 ]
Fadel, E. [1 ,3 ,4 ]
Mercier, O. [1 ,3 ,4 ]
Montani, D. [1 ,2 ,4 ]
Humbert, M. [1 ,2 ,4 ]
机构：
[1] Univ Paris Saclay, Fac Med, F-94270 Le Kremlin Bicetre, France
[2] Hop Bicetre, Ctr Reference Hypertens Plum, F-94270 Le Kremlin Bicetre, France
[3] Hop Marie Lannelongue, Grp Hosp Paris St Joseph, F-92350 Le Plessis Robinson, France
[4] Inserm UMR S 999, F-94270 Le Kremlin Bicetre, France
来源：
BULLETIN DE L ACADEMIE NATIONALE DE MEDECINE | 2023年 / 207卷 / 01期
关键词：
Hypertension; Pulmonary; Thromboembolism; Endarterectomy; Angioplasty; Balloon; RISK-FACTORS; ANGIOPLASTY; RIOCIGUAT;
D O I：
10.1016/j.banm.2022.10.010
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare complication of a frequent disease. The occlusion of pulmonary arteries by organized fibrotic material in com-bination with a secondary microvasculopathy of vessels < 500 & mu;, like that observed in idiopathic PAH, leads to increased pulmonary vascular resistance and progressive right heart failure. Today the prognostic of this disease has markedly improved with the availability, in addition to lifelong anticoagulation, of different treatment modalities including surgery, angioplasty and medical therapy with PAH drugs according to the localization and characteristics of observed lesions. & COPY; 2022 l'Academie nationale de medecine. Published by Elsevier Masson SAS. All rights reserved.
引用
收藏
页码：32 / 37
页数：6
相关论文
共 50 条
  • [1] Pathophysiology and Treatment of Chronic Thromboembolic Pulmonary Hypertension
    Otani, Naoyuki
    Watanabe, Ryo
    Tomoe, Takashi
    Toyoda, Shigeru
    Yasu, Takanori
    Nakamoto, Takaaki
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2023, 24 (04)
  • [2] Bosentan for Treatment of Inoperable Chronic Thromboembolic Pulmonary Hypertension
    Jais, Xavier
    D'Armini, Andrea M.
    Jansa, Pavel
    Torbicki, Adam
    Delcroix, Marion
    Ghofrani, Hossein A.
    Hoeper, Marius M.
    Lang, Irene M.
    Mayer, Eckhard
    Pepke-Zaba, Joanna
    Perchenet, Loic
    Morganti, Adele
    Simonneau, Gerald
    Rubin, Lewis J.
    JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2008, 52 (25) : 2127 - 2134
  • [3] CHRONIC THROMBOEMBOLIC PULMONARY HYPERTENSION: LONG TERM OUTCOMES IN SURGICAL AND NON-SURGICAL PATIENTS
    Quadery, S. R.
    Condliffe, R. A.
    Billings, C.
    Thompson, R.
    Elliot, C. A.
    Charalampopolous, A.
    Hurdman, J.
    Hamilton, N.
    Armstrong, I.
    Sephton, P.
    Sabroe, I.
    Swift, A.
    Wild, J.
    Kiely, D. G.
    THORAX, 2016, 71 : A98 - A98
  • [4] The actuarial survival analysis of the surgical and non-surgical therapy regimen for chronic thromboembolic pulmonary hypertension
    Hui-Li Gan
    Jian-Qun Zhang
    Ping Bo
    Qi-Wen Zhou
    Sheng-Xun Wang
    Journal of Thrombosis and Thrombolysis, 2010, 29 : 25 - 31
  • [5] The actuarial survival analysis of the surgical and non-surgical therapy regimen for chronic thromboembolic pulmonary hypertension
    Gan, Hui-Li
    Zhang, Jian-Qun
    Bo, Ping
    Zhou, Qi-Wen
    Wang, Sheng-Xun
    JOURNAL OF THROMBOSIS AND THROMBOLYSIS, 2010, 29 (01) : 25 - 31
  • [6] Ambrisentan for treatment of inoperable chronic thromboembolic pulmonary hypertension (CTEPH)
    Escribano-Subias, Pilar
    Bendjenana, Hakim
    Curtis, Paula S.
    Lang, Irene
    Noordegraaf, Anton Vonk
    PULMONARY CIRCULATION, 2019, 9 (02)
  • [7] Surgical treatment of chronic thromboembolic pulmonary hypertension
    Mayer, Eckhard
    SWISS MEDICAL WEEKLY, 2006, 136 (31-32) : 491 - 497
  • [8] Surgical treatment of chronic thromboembolic pulmonary hypertension
    Dartevelle, P
    Fadel, E
    Mussot, S
    Cerrina, J
    Ladurie, EL
    Lehouerou, D
    Parquin, E
    Paul, JE
    Musset, D
    Humbert, M
    Sitbon, O
    Parent, E
    Simonneau, G
    PRESSE MEDICALE, 2005, 34 (19): : 1475 - 1486
  • [9] Surgical treatment of chronic thromboembolic pulmonary hypertension
    Jenkins, David P.
    Madani, Michael
    Mayer, Eckhard
    Kerr, Kim
    Kim, Nic
    Klepetko, Walter
    Morsolinl, Marco
    Dartevelle, Philippe
    EUROPEAN RESPIRATORY JOURNAL, 2013, 41 (03) : 735 - 742
  • [10] The pathophysiology of chronic thromboembolic pulmonary hypertension
    Simonneau, Gerald
    Torbicki, Adam
    Dorfmuller, Peter
    Kim, Nick
    EUROPEAN RESPIRATORY REVIEW, 2017, 26 (143):
12345