Long non-coding RNAs in multiple myeloma (Review)

被引：4

作者：

Yang, Chenbo ^{[1
,2
]}

Liang, Yinghao ^{[2
,3
,4
]}

Shu, Jiao ^{[1
,2
]}

Wang, Shuaiyuan ^{[1
,2
]}

Hong, Yichen ^{[2
,3
,4
]}

Chen, Kuisheng ^{[1
,2
]}

Sun, Miaomiao ^{[1
,2
]}

机构：

[1] Zhengzhou Univ, Dept Pathol, Affiliated Hosp 1, 1 Jianshe Dong Rd, Zhengzhou 450052, Henan, Peoples R China

[2] Zhengzhou Univ, Henan Key Lab Tumor Pathol, Zhengzhou 450052, Henan, Peoples R China

[3] BGI Coll, Zhengzhou 450052, Henan, Peoples R China

[4] Henan Inst Med & Pharmaceut Sci, Zhengzhou 450052, Henan, Peoples R China

来源：

INTERNATIONAL JOURNAL OF ONCOLOGY | 2023年 / 62卷 / 06期

基金：

中国国家自然科学基金;

关键词：

multiple myeloma; long non-coding RNA; molecular mechanism; tumor progression; prognosis; drug resistance; INTERNATIONAL STAGING SYSTEM; PROMOTES CELL-GROWTH; PROTEASOME INHIBITORS; DRUG-RESISTANCE; WORKING GROUP; PROLIFERATION; EXPRESSION; DISEASE; IDENTIFICATION; PROGRESSION;

D O I：

10.3892/ijo.2023.5517

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Multiple myeloma (MM) is one of the three major malignancies of the hematological system in middle-aged and older individuals. The incidence of MM increases with age and due to its drug resistance and high recurrence, MM seriously harms human health. Long non-coding RNAs (lncRNAs) are RNA molecules with a length of >200 nt and rarely encode proteins. Numerous studies reported that lncRNAs regulate carcinogenesis and cancer progression. MM-associated lncRNAs affect features of tumor cells, including proliferation, apoptosis, adhesion and treatment resistance. The present review aims to summarize the latest findings on the roles of lncRNAs in MM to deepen the understanding of this field and provide insight for developing specific diagnostic tools and effective treatment strategies for MM, including novel biomarkers and targeted lncRNA therapeutics.

引用

页数：16

共 50 条

[1] LONG NON-CODING RNAS IN MULTIPLE MYELOMA
Sedlarikova, L.
Gromesova, B.
Kubaczkova, V.
Radova, L.
Almasi, M.
Penka, M.
Adam, Z.
Pour, L.
Krejci, M.
Sevcikova, S.
Hajek, R.
HAEMATOLOGICA, 2016, 101 : 518 - 518
[2] Long Non-Coding RNAs in Multiple Myeloma
Butova, Romana
Vychytilova-Faltejskova, Petra
Souckova, Adela
Sevcikova, Sabina
Hajek, Roman
NON-CODING RNA, 2019, 5 (01)
[3] Long Non-Coding RNAs in Multiple Myeloma
Nobili, Lucia
Ronchetti, Domenica
Agnelli, Luca
Taiana, Elisa
Vinci, Cristina
Neri, Antonino
GENES, 2018, 9 (02):
[4] The role of long non-coding RNAs in multiple myeloma
Cui, Yu-Shan
Song, Yong-Ping
Fang, Bai-Jun
EUROPEAN JOURNAL OF HAEMATOLOGY, 2019, 103 (01) : 3 - 9
[5] Long Non-Coding RNAs Annotation and Their Involvement in Multiple Myeloma
Carrasco, Arantxa
Ezponda, Teresa
Meydan, Cem
Kulis, Marta
Ordonez, Raquel
Garate, Leire
Segura, Victor
Alignani, Diego
Paiva, Bruno
Miguel, Jesus San
Subero, Jose I. Martin
Melnick, Ari
Prosper, Felipe
Agirre, Xabier
BLOOD, 2016, 128 (22)
[6] Epigenetic Role of Long Non-coding RNAs in Multiple Myeloma
Nikita Mehra
Subhiksha Sundaram
Parth Shah
Arunagiri Kuha Deva Magendhra Rao
Current Oncology Reports, 2025, 27 (1) : 37 - 44
[7] A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma
Ronchetti, Domenica
Agnelli, Luca
Pietrelli, Alessandro
Todoerti, Katia
Manzoni, Martina
Taiana, Elisa
Neri, Antonino
SCIENTIFIC REPORTS, 2018, 8
[8] A COMPENDIUM OF LONG NON-CODING RNAS TRANSCRIPTIONAL FINGERPRINT IN MULTIPLE MYELOMA
Taiana, E.
Ronchetti, D.
Agnelli, L.
Todoerti, K.
Manzoni, M.
Vinci, C.
Favasuli, V
Pelizzoni, F.
Neri, A.
HAEMATOLOGICA, 2018, 103 : 15 - 15
[9] A compendium of long non-coding RNAs transcriptional fingerprint in multiple myeloma
Domenica Ronchetti
Luca Agnelli
Alessandro Pietrelli
Katia Todoerti
Martina Manzoni
Elisa Taiana
Antonino Neri
Scientific Reports, 8
[10] The Multiple Myeloma Landscape: Epigenetics and Non-Coding RNAs
Coira, Isabel F.
Rincon, Rafael
Cuendet, Muriel
CANCERS, 2022, 14 (10)

← 1 2 3 4 5 →