Clinical, histopathological and ultrastructural features of human monkeypox infection in the 2022 outbreak: report of a case with immunohistochemistry for vaccinia virus

被引：4
|
作者：
Prieto-Perez, L. [1 ]
Montana, A. M. Vicente [2 ]
Santonja, C. [1 ]
Fortes, J. [1 ]
Garcia-Fresnadillo, D. [3 ,4 ]
Jo-Velasco, M. [1 ]
Requena, L. [1 ]
Cabello, A. [1 ]
Fernandez-Roblas, R. [1 ]
Alvarez, B. [1 ]
Carrillo, I [1 ]
Gorgolas, M. [1 ]
机构：
[1] Univ Hosp Fdn Jimenez Diaz, Ave Reyes Catolicos 2, Madrid 28040, Spain
[2] Univ Complutense Madrid, ICTS Natl Ctr Electron Microscopy, Madrid, Spain
[3] Univ Hosp Puerta Hierro, Majadahonda, Spain
[4] Univ Hosp Puerta Hierro, Madrid, Spain
来源：
CLINICAL AND EXPERIMENTAL DERMATOLOGY | 2023年 / 48卷 / 01期
关键词：
D O I：
10.1093/ced/llac020
中图分类号：
R75 [皮肤病学与性病学];
学科分类号：
100206 ;
摘要：
Human monkeypox (HMPX) is an emerging viral zoonosis that has now become the most prevalent Orthopoxvirus worldwide.1 The Poxviridae family is formed by large, double-stranded DNA viruses that replicate in vertebrate cells. Currently, there is a substantial outbreak of HMPX, with more than 64 200 cases reported to date.2 Reports on the histology and ultrastructure of the current HMPX are currently scarce.3 We describe the clinical, histological, immunohistochemical and ultrastructural features of the current HMPX virus, emphasizing the applicability of both transmission electron microscopy (TEM) and immunohistochemistry (IHC) for a fast visualization and identification of viruses. © 2023 Oxford University Press. All rights reserved.
引用
收藏
页码：60 / 63
页数：4
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