Mixed reality holograms for percutaneous lead extraction of cardiac implantable electronic devices

To assess the potential of mixed reality holograms (MixR) based on CT images to improve percutaneous lead extraction (PLE) planning and intraoperative assistance. This was a prospective, controlled, single-centre study. Five patients with CIED infection for PLE were included in the study. Conventional imaging (chest radiograph and CT) and MixR holograms were evaluated for preoperative planning to identify common complications such as vascular thrombosis, broken leads, loops, kinking, fibrosis along the wires, and perforation of cardiovascular structures. The degree of difficulty of the procedure was estimated based on potential complications. After the PLE procedure, the level of concordance between conventional imaging and MixR holograms with intraoperative findings was evaluated. The utility of MixR intraoperative guidance was also assessed. MixR holograms demonstrated a very high correlation in predicting the presence of loops, kinking, and fibrosis compared to conventional imaging, which showed a low-to-high correlation. MixR also showed a high correlation in estimating the degree of difficulty of the procedure compared to conventional imaging, which tended to underestimate it. The surgeon who performed the PLE agreed that MixR was helpful during intraoperative assistance. MixR holograms based on CT images are an effective tool for understanding cardiovascular anatomy and detecting potential areas of complications. MixR may be used as a complementary tool for both preoperative planning and intraoperative assistance in PLE procedures.Graphical abstractMixed reality holograms for intraprocedural intervention assistance.