Cancer stem cell immunoediting by IFNγ

被引：0
|
作者：
Galassi, Claudia [1 ]
Galluzzi, Lorenzo [1 ,2 ,3 ]
机构：
[1] Weill Cornell Med Coll, Dept Radiat Oncol, New York, NY 10004 USA
[2] Sandra & Edward Meyer Canc Ctr, New York, NY 10065 USA
[3] Caryl & Israel Englander Inst Precis Med, New York, NY 10027 USA
来源：
CELL DEATH & DISEASE | 2023年 / 14卷 / 08期
关键词：
D O I：
10.1038/s41419-023-06079-2
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
The secretion of interferon gamma (IFNG, best known as IFN & gamma;) by immune effector cells generally mediates potent anticancer effects. Recent data from Beziaud et al. demonstrate that-at least in some circumstances-IFN & gamma; can edit the breast cancer microenvironment to promote stemness, disease progression and resistance to (immuno)therapy.
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页数：3
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