Nf1 Deficiency-induced Senescence in Osteoprogenitor Cells and Therapeutic Implications for the Treatment of NF1 Pseudarthrosis

被引:0
|
作者
Cuko, Efrosini [1 ]
Madel, Maria-Bernadette [1 ]
Nikolos, Fotis [2 ]
Couasnay, Greig [3 ]
Rios, Jonathan [4 ]
Elefteriou, Florent [5 ]
机构
[1] Baylor Coll Med, Orthoped Surg, Houston, TX USA
[2] Cedars Sinai Med Ctr, Samuel Oschin Canc Ctr, Los Angeles, CA USA
[3] Baylor Coll Med, Orthoped Surg, Houston, TX USA
[4] Scottish Rite Children, Ctr Pediat Bone Biol & Translat Res, Dallas, TX USA
[5] Baylor Coll Med, Mol & Human Genet, Houston, TX USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
FRI-695
引用
收藏
页码:96 / 96
页数:1
相关论文
共 50 条
  • [41] Motor deficits and neurofibromatosis type 1 (NF1)-associated MRI impairments in a mouse model of NF1
    Robinson, Ari
    Kloog, Yoel
    Stein, Reuven
    Assaf, Yaniv
    NMR IN BIOMEDICINE, 2010, 23 (10) : 1173 - 1180
  • [42] Somatic neurofibromatosis type 1 (NF1) inactivation events in cutaneous neurofibromas of a single NF1 patient
    Emmerich, Denise
    Zemojtel, Tomasz
    Hecht, Jochen
    Krawitz, Peter
    Spielmann, Malte
    Kuehnisch, Jirko
    Kobus, Karolina
    Osswald, Monika
    Heinrich, Verena
    Berlien, Peter
    Mueller, Ute
    Mautner, Victor-F
    Wimmer, Katharina
    Robinson, Peter N.
    Vingron, Martin
    Tinschert, Sigrid
    Mundlos, Stefan
    Kolanczyk, Mateusz
    EUROPEAN JOURNAL OF HUMAN GENETICS, 2015, 23 (06) : 870 - 873
  • [43] Developmental Trends in Individuals with NF1 and Noona phenotype (NFNS) Compared with Matched NF1 and Controls
    Paltin, I
    Walsh, K.
    Rosenbaum, K.
    Copenheaver, D.
    Zand, D.
    Kardel, P.
    Acosta, M.
    Packer, R.
    ARCHIVES OF CLINICAL NEUROPSYCHOLOGY, 2010, 25 (06) : 508 - 509
  • [44] Illegitimate splicing of the NF1 gene in healthy individuals mimics mutation-induced splicing alterations in NF1 patients
    Wimmer, K
    Eckart, M
    Rehder, H
    Fonatsch, C
    HUMAN GENETICS, 2000, 106 (03) : 311 - 313
  • [45] Illegitimate splicing of the NF1 gene in healthy individuals mimics mutation-induced splicing alterations in NF1 patients
    Katharina Wimmer
    Markus Eckart
    Helga Rehder
    Christa Fonatsch
    Human Genetics, 2000, 106 (3) : 311 - 313
  • [46] Identification of transcriptional mechanisms specific to of NF1 gene deficiency
    Sun, Daochun
    Kraniak, Janice
    Mattingly, Raymond
    Tainsky, Michael A.
    CANCER RESEARCH, 2010, 70
  • [47] Methylation status of NF1 promoter in benign tumours from 10 unrelated NF1 patients
    Horan, M
    Upadhyaya, M
    JOURNAL OF MEDICAL GENETICS, 1999, 36 : S77 - S77
  • [48] Double inactivation of the NF1 gene in tibial pseudarthrosis from an individual with neurofibromatosis type 1
    Viskochil, DH
    Nielsen-Rogers, T
    Zhou, H
    Randall, L
    Stevenson, D
    Messiaen, L
    BONE, 2005, 36 : S79 - S80
  • [49] Nf1 haploinsufficiency and Icsbp deficiency synergize in the development of leukemias
    Koenigsmann, Jessica
    Rudolph, Cornelia
    Sander, Sandrine
    Kershaw, Olivia
    Gruber, Achim D.
    Bullinger, Lars
    Schlegelberger, Brigitte
    Carstanjen, Dirk
    BLOOD, 2009, 113 (19) : 4690 - 4701
  • [50] Nf1 has an essential role in endothelial cells
    Gitler, AD
    Zhu, Y
    Ismat, FA
    Lu, MM
    Yamauchi, Y
    Parada, LF
    Epstein, JA
    NATURE GENETICS, 2003, 33 (01) : 75 - 79