Post-dialysis fatigue and serum S100B protein in patients on chronic hemodialysis. A pilot study

被引：2
|
作者：
Bossola, Maurizio [1 ,2 ]
Picca, Anna [2 ,3 ]
Marzetti, Emanuele [2 ,3 ]
Pepe, Gilda [2 ,4 ]
Antocicco, Manuela [3 ]
Di Stasio, Enrico [2 ,5 ]
机构：
[1] Policlin Univ Fdn A Gemelli IRCCS, Serv Emodialisi, Rome, Italy
[2] Univ Cattolica Sacro Cuore, Largo A Gemelli 8, I-00168 Rome, Italy
[3] Policlin Univ Fdn A Gemelli IRCCS, Dipartimento Geriatria Neurosci & Ortopedia, Rome, Italy
[4] Policlin Univ Fdn Policlin A Gemelli IRCCS, Div Chirurg Urgenza, Rome, Italy
[5] Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Laboratorist & Infettivol, UOC Chim Biochim & Biol Mol Clin, Rome, Italy
来源：
THERAPEUTIC APHERESIS AND DIALYSIS | 2023年 / 27卷 / 03期
关键词：
blood-brain barrier; cytokines; fatigue; hemodialysis; S100B protein; MULTIPLE-SCLEROSIS; SICKNESS; MARKERS; INFLAMMATION; MECHANISMS; EXPRESSION; DEPRESSION; VARIABLES; SYMPTOMS; RECOVERY;
D O I：
10.1111/1744-9987.13944
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Background Aim of the present study was to assess whether post-dialysis fatigue (PDF) may be related to pre- or post-dialysis levels of serum S100B protein. Hemodialysis patients (HD) who answered to be fatigued after their hemodialysis sessions when asked: "Do you feel worse after dialysis? if they answered yes" were considered to suffer from PDF. Serum Interleukins (IL-1 beta, IL-6, IL-10), TNF-alpha and S100B were assessed by ELISA kit. Results Thirty HD patients were studied: 22 (73.4%) reported to suffer from PDF. Serum S100B post-dialysis levels (median [IQR] = 17.4 mu g [7.1 to 30.9]) were significantly higher than serum S100B pre-dialysis levels (median [IQR] = 5 mu g [1.4 to 22.1]; p = 0.0001). S100B post-dialysis was significantly higher than S100B pre-dialysis either in patients with PDF or without PDF. Conclusions Pre- and post-dialysis values of serum S100B and its delta did not differ significantly between patients with and without PDF and were not associated with the length of the TIRD in patients on chronic hemodialysis.
引用
收藏
页码：471 / 479
页数：9
相关论文
共 50 条
  • [31] Serum S100B protein is increased in fasting rats
    Netto, Cristina B. O.
    Conte, Sabrina
    Leite, Marina C.
    Pires, Caroline
    Martins, Tiago L.
    Vidal, Penelope
    Benfato, Mara S.
    Giugliani, Roberto
    Gonçalves, Carlos-Alberto
    ARCHIVES OF MEDICAL RESEARCH, 2006, 37 (05) : 683 - 686
  • [32] Peripheral, Interictal Serum S100B Levels are Not Increased in Chronic Migraine Patients
    Riesco, Nuria
    Cernuda-Morollon, Eva
    Martinez-Camblor, Pablo
    Perez-Pereda, Sara
    Pascual, Julio
    HEADACHE, 2020, 60 (08): : 1705 - 1711
  • [33] Is serum S100B protein an useful biomarker in migraine?
    Celikbilek, Asuman
    Sabah, Seda
    Tanik, Nermin
    Ak, Hakan
    Atalay, Tugay
    Yilmaz, Neziha
    NEUROLOGICAL SCIENCES, 2014, 35 (08) : 1197 - 1201
  • [34] Neurodevelopment and phenotype-modulating functions of S100B protein: A pilot study
    Davydov, D. M.
    Lobanov, A. V.
    Morozov, S. G.
    Gribova, I. E.
    Murashev, A. N.
    PHYSIOLOGY & BEHAVIOR, 2015, 140 : 188 - 196
  • [35] Serum S100B protein as a marker of severity in Covid-19 patients
    Antonio Aceti
    Lory Marika Margarucci
    Elena Scaramucci
    Massimiliano Orsini
    Gerardo Salerno
    Gabriele Di Sante
    Gianluca Gianfranceschi
    Rosa Di Liddo
    Federica Valeriani
    Francesco Ria
    Maurizio Simmaco
    Pier Paolo Parnigotto
    Matteo Vitali
    Vincenzo Romano Spica
    Fabrizio Michetti
    Scientific Reports, 10
  • [36] Personal abilities in patients undergoing peritoneal dialysis and hemodialysis.: A pilot study using the existence scale
    Schwaiger, Johannes P.
    Kopriva-Altfahrt, Gertrude
    Soellner, Wolfgang
    Koenig, Paul
    WIENER KLINISCHE WOCHENSCHRIFT, 2007, 119 (11-12) : 350 - 354
  • [37] Serum S100B protein as a marker of severity in Covid-19 patients
    Aceti, Antonio
    Margarucci, Lory Marika
    Scaramucci, Elena
    Orsini, Massimiliano
    Salerno, Gerardo
    Di Sante, Gabriele
    Gianfranceschi, Gianluca
    Di Liddo, Rosa
    Valeriani, Federica
    Ria, Francesco
    Simmaco, Maurizio
    Parnigotto, Pier Paolo
    Vitali, Matteo
    Romano Spica, Vincenzo
    Michetti, Fabrizio
    SCIENTIFIC REPORTS, 2020, 10 (01)
  • [38] High serum protein S100B levels in brain-dead patients
    S Korfias
    I Dimopoulou
    A Anthi
    C Psachoulia
    L Kiriou
    C Roussos
    DE Sakas
    Critical Care, 6 (Suppl 1):
  • [39] Theoretical study on binding of S100B protein
    Gieldon, Artur
    Mori, Mattia
    Del Conte, Rebecca
    JOURNAL OF MOLECULAR MODELING, 2007, 13 (11) : 1123 - 1131
  • [40] Theoretical study on binding of S100B protein
    Artur Gieldon
    Mattia Mori
    Rebecca Del Conte
    Journal of Molecular Modeling, 2007, 13
12345