Loncastuximab Tesirine Demonstrated Substantial Single-Agent Efficacy and Manageable Safety Profile in Heavily Pretreated Chinese Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)

被引:2
|
作者
Lin, Ningjing [1 ]
Sun, Xiuhua [2 ]
Zhou, Hui [3 ]
Zou, Liqun [4 ]
Zhou, Keshu [5 ]
Liu, Lihong [6 ]
Yang, Haiyan [7 ]
Hu, Kai [8 ]
Cai, Qingqing [9 ]
Liu, Yao [10 ]
Jin, Jie [11 ]
Zhang, Liling [12 ]
Li, Wenyu [13 ]
Guo, Ye [14 ]
Yang, Wei [15 ]
Luo, Feng [16 ]
Li, Yanyan [16 ]
Zhang, Mengqi [16 ]
Lu, Feinan [16 ]
Song, Yuqin [17 ]
Zhu, Jun [18 ]
机构
[1] Beijing Canc Hosp, Dept Lymphat Oncol, Beijing, Peoples R China
[2] Dalian Med Univ, Hosp 2, Dalian, Peoples R China
[3] Cent South Univ, Hunan Canc Hosp, Affiliated Canc Hosp, Xiangya Sch Med, Changsha, Peoples R China
[4] Sichuan Univ, West China Hosp, Chengdu, Peoples R China
[5] Zhengzhou Univ, Henan Canc Hosp, Dept Hematol, Canc Hosp, Zhengzhou, Peoples R China
[6] Hebei Med Univ, Hosp 4, Shijiazhuang, Hebei, Peoples R China
[7] Zhejiang Canc Hosp, Dept Lymphat Oncol, Hangzhou, Peoples R China
[8] Beijing Boren Hosp, Dept Adult Lymphoma, Beijing, Peoples R China
[9] Sun Yat Sen Univ, Canc Cente, Guangzhou, Peoples R China
[10] Chongqing Univ, Canc Hosp, Chongqing, Peoples R China
[11] Zhejiang Univ, Dept Hematol, Affiliated Hosp 1, Sch Med, Hangzhou, Peoples R China
[12] Huazhong Univ Sci & Technol, Union Hosp, Tongji Med Coll, Ctr Canc, Wuhan, Peoples R China
[13] Guangdong Prov Peoples Hosp, Guangzhou, Peoples R China
[14] Shanghai East Hosp, Shanghai, Peoples R China
[15] China Med Univ, Dept Hematol, Shengjing Hosp, Shenyang, Peoples R China
[16] Overland Pharmaceut, Shanghai, Peoples R China
[17] Peking Univ, Key Lab Carcinogenesis & Translat Res, Dept Lymphoma, Minist Educ Beijing,Canc Hosp & Inst, Beijing, Peoples R China
[18] Peking Univ, Canc Hosp, Beijing, Peoples R China
关键词
D O I
10.1182/blood-2023-173645
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
引用
收藏
页数:4
相关论文
共 50 条
  • [21] Magrolimab in Combination with Rituximab plus Chemotherapy in Patients with Relapsed or Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
    Maakaron, Joseph
    Asch, Adam S.
    Popplewell, Leslie L.
    Collins, Graham P.
    Flinn, Ian W.
    Ghosh, Nilanjan
    Keane, Colin
    Ku, Matthew
    Mehta, Amitkumar
    Roschewski, Mark
    O'Hear, Carol
    Ren, Xuehan
    Villa, Bertha
    Lal, Indu
    Smith, Sonali M.
    Advani, Ranjana H.
    BLOOD, 2022, 140 : 3728 - 3730
  • [22] A Phase 2b Study of Selinexor in Patients with Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL)
    Kalakonda, Nagesh
    Cavallo, Federica
    Follows, George
    Goy, Andre
    Vermaat, Joost S. P.
    Casasnovas, Olivier
    Lavee, Orly
    Maerevoet, Marie
    Zijlstra, Josee
    Bakhshi, Sameer
    Bouabdallah, Reda
    Choquet, Sylvain
    Gurion, Ronit
    Hill, Brian
    Jaeger, Ulrich
    Sancho, Juan-Manuel
    Schuster, Michael
    Thieblemont, Catherine
    De la Cruz, Fatima
    Egyed, Miklos
    Mishra, Sourav
    Offner, Fritz
    Vassilakopoulos, Theodoros
    Warzocha, Krzysztof
    McCarthy, Daniel
    Ma, Xiwen
    Corona, Kelly
    Saint-Martin, Jean-Richard
    Joshi, Anita
    Shah, Jatin
    Van den Neste, Eric
    Canales, Miguel
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2019, 19 : S248 - S249
  • [23] Understanding the patient experience in follicular lymphoma (FL), relapsed/refractory FL (R/R FL), and relapsed/refractory diffuse large B-cell lymphoma (R/R DLBCL)
    Bell, Jill A.
    Cherepanov, Dasha
    Revicki, Dennis
    Speck, Rebecca M.
    Swett, Laura
    Stumpo, Kate
    Rong, Yuanxin
    Gordon, Leo I.
    QUALITY OF LIFE RESEARCH, 2019, 28 : S67 - S68
  • [24] Loncastuximab tesirine in Chinese patients with relapsed or refractory diffuse large B-cell lymphoma: a multicenter, open-label, single-arm, phase II trial
    Lin, Ningjing
    Sun, Xiuhua
    Zhou, Hui
    Zou, Liqun
    Zhou, Keshu
    Liu, Lihong
    Yang, Haiyan
    Hu, Kai
    Cai, Qingqing
    Liu, Yao
    Jin, Jie
    Zhang, Liling
    Li, Wenyu
    Guo, Ye
    Yang, Wei
    Luo, Feng
    Wang, Zhenguang
    Zhu, Rong
    Yang, Lei
    Song, Dan
    Song, Yuqin
    Zhu, Jun
    HAEMATOLOGICA, 2025, 110 (03) : 683 - 692
  • [25] Patient, Caregiver, and Physician Preferences for Treatment of Relapsed or Refractory Diffuse Large B-Cell Lymphoma (R/R DLBCL)
    Vukcevic, Mirko
    Yung, Mallory
    Khan, Mali
    Houpt, Bethany
    Schnell, Frederick
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 : S376 - S377
  • [26] The Burden of Relapsed/Refractory (R/R) Diffuse Large B-Cell Lymphoma (DLBCL): A Systematic Literature Review (SLR)
    Lenz, Georg
    Rutherford, Sarah C.
    Davies, Andrew
    Zinzani, Pier Luigi
    Salles, Gilles
    Hasskarl, Jens
    Margunato-Debay, Sandra
    Rodrigues, Filipe
    Nientker, Lisette
    Balradj, Janita
    Alleman, Cathelijne
    BLOOD, 2018, 132
  • [27] Patient, caregiver, and physician preferences for treatment of relapsed or refractory diffuse large B-cell lymphoma (R/R DLBCL).
    Vukcevic, Mirko
    Yung, Mallory
    Khan, Maliha
    Schnell, Frederick Mark
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16) : E18710 - E18710
  • [28] Inpatient treatment of relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL): A health economic perspective
    Moertl, Bernhard
    Dreyling, Martin
    Schmidtl, Christian
    Hoster, Eva
    Schoel, Wolfgang
    V. Bergwelt-Baildon, Michael
    Berger, Karin
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 (07): : 474 - 482
  • [29] Interim evaluation of a targeted radiotherapeutic, CLR 131, in relapsed/refractory diffuse large B-cell lymphoma patients (R/R DLBCL)
    Longcor, J.
    Oliver, K.
    Friend, J.
    Callandar, N.
    ANNALS OF ONCOLOGY, 2019, 30 : 435 - 435
  • [30] Health-Related Quality of Life, Symptoms, and Tolerability of Loncastuximab Tesirine in Patients With Relapsed or Refractory Diffuse Large B-Cell Lymphoma
    Spira, Alexander
    Zhou, Xiaolei
    Chen, Lei
    Gnanasakthy, Ari
    Wang, Luqiang
    Ungar, David
    Curiel, Rafael
    Liao, Laura
    Radford, John
    Kahl, Brad
    CLINICAL LYMPHOMA MYELOMA & LEUKEMIA, 2022, 22 (03): : 158 - 168