CRISPR nuclease off-target activity and mitigation strategies (vol 4, 1050507, 2022)

被引：1
|
作者：
Wienert, Beeke [1 ]
Cromer, M. Kyle [2 ,3 ,4 ]
机构：
[1] Graphite Bio Inc, San Francisco, CA USA
[2] Univ Calif San Francisco, Dept Surg, San Francisco, CA 94143 USA
[3] Univ Calif San Francisco, Dept Bioengn & Therapeut Sci, San Francisco, CA 94143 USA
[4] Univ Calif San Francisco, Eli & Edythe Broad Ctr Regenerat Med, San Francisco, CA 94143 USA
来源：
FRONTIERS IN GENOME EDITING | 2023年 / 4卷
关键词：
gene therapy; off-target activity; in vivo delivery; genome editing; CRISPR/Cas9; next-generating sequencing;
D O I：
10.3389/fgeed.2022.1112956
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
引用
收藏
页数：1
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