Amino alcohol-derived chiral stationary phases

被引：3

作者：

Seog, David Jin Han ^{[1
]}

Kien, Nguyen van ^{[1
]}

Ryoo, Jae Jeong ^{[1
,2
]}

机构：

[1] Kyungpook Natl Univ, Dept Chem Educ, Daegu, South Korea

[2] Kyungpook Natl Univ, Dept Chem Educ, Daegu 702701, South Korea

来源：

CHIRALITY | 2023年 / 35卷 / 10期

关键词：

amino alcohol; chiral separation; chiral stationary phases; HPLC; symmetric CSPs; LIQUID-CHROMATOGRAPHIC RESOLUTION; LIGAND-EXCHANGE; OPTICAL RESOLUTION; ENANTIOSELECTIVE RECOGNITION; ABSOLUTE-CONFIGURATION; N-ACYLARYLALKYLAMINES; MOLECULAR RECOGNITION; ASYMMETRIC-SYNTHESIS; HIGHLY EFFICIENT; SILICA-GEL;

D O I：

10.1002/chir.23574

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

An updated minireview of chiral stationary phases (CSPs) based on amino alcohols is presented. In this minireview, we focused on amino alcohols as starting materials in preparation of chiral catalysts for asymmetric organic synthesis and CSPs for chiral separations. Among the various CSPs, we summarized the important developments and applications of the amino alcohol-based Pirkle-type CSPs, ligand exchange CSPs, alpha-amino acid-derived amino alcohol CSPs, and symmetric CSPs from their first appearance to the present day to propose ideas for the development of new CSPs with improved performance.

引用

页码：739 / 752

页数：14

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